3TMQ
Crystal structure of a 2-dehydro-3-deoxyphosphooctonate aldolase from Burkholderia pseudomallei in complex with D-arabinose-5-phosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE A5P C 282 |
| Chain | Residue |
| A | ARG118 |
| C | ALA211 |
| C | SER212 |
| C | ASP248 |
| C | NO3283 |
| C | NO3284 |
| C | EDO287 |
| C | HOH342 |
| C | HOH371 |
| C | ASN24 |
| C | LYS58 |
| C | ASN60 |
| C | ARG61 |
| C | SER62 |
| C | HIS200 |
| C | GLN203 |
| C | ARG205 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE A5P A 282 |
| Chain | Residue |
| A | ASN24 |
| A | LYS58 |
| A | ASN60 |
| A | ARG61 |
| A | SER62 |
| A | HIS200 |
| A | GLN203 |
| A | ARG205 |
| A | ALA211 |
| A | SER212 |
| A | ASP248 |
| A | NO3283 |
| A | NO3284 |
| A | HOH312 |
| A | HOH317 |
| A | HOH519 |
| C | ARG118 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE NO3 A 283 |
| Chain | Residue |
| A | LYS53 |
| A | SER55 |
| A | LYS58 |
| A | GLN111 |
| A | LYS136 |
| A | HIS200 |
| A | PHE235 |
| A | A5P282 |
| A | NO3284 |
| A | HOH319 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE NO3 A 284 |
| Chain | Residue |
| A | PRO113 |
| A | ALA114 |
| A | LYS136 |
| A | ARG166 |
| A | A5P282 |
| A | NO3283 |
| A | HOH313 |
| A | HOH319 |
| A | HOH356 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE NO3 C 283 |
| Chain | Residue |
| C | LYS53 |
| C | SER55 |
| C | LYS58 |
| C | GLN111 |
| C | LYS136 |
| C | HIS200 |
| C | PHE235 |
| C | A5P282 |
| C | NO3284 |
| C | HOH306 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE NO3 C 284 |
| Chain | Residue |
| C | PRO113 |
| C | ALA114 |
| C | LYS136 |
| C | ARG166 |
| C | A5P282 |
| C | NO3283 |
| C | EDO287 |
| C | HOH306 |
| C | HOH312 |
| C | HOH373 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NO3 C 285 |
| Chain | Residue |
| C | ASN13 |
| C | PHE182 |
| C | ARG183 |
| C | VAL194 |
| C | GLY230 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 C 286 |
| Chain | Residue |
| C | ASP173 |
| C | ASN174 |
| C | GLN203 |
| C | CYS204 |
| C | HOH359 |
| C | HOH389 |
| C | HOH416 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NO3 A 285 |
| Chain | Residue |
| A | ASN13 |
| A | PHE182 |
| A | ARG183 |
| A | VAL194 |
| A | GLY230 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NO3 D 282 |
| Chain | Residue |
| D | LYS53 |
| D | SER55 |
| D | ASP93 |
| D | GLN111 |
| D | LYS136 |
| D | HIS200 |
| D | PHE235 |
| D | EDO283 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 B 282 |
| Chain | Residue |
| B | SER169 |
| B | PHE170 |
| B | GLY171 |
| B | HOH431 |
| D | SER169 |
| D | GLY171 |
| A | PHE170 |
| site_id | BC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE NO3 B 283 |
| Chain | Residue |
| B | LYS53 |
| B | SER55 |
| B | LYS58 |
| B | ASP93 |
| B | GLN111 |
| B | LYS136 |
| B | HIS200 |
| B | PHE235 |
| B | EDO284 |
| site_id | BC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO C 287 |
| Chain | Residue |
| A | ARG118 |
| C | ARG166 |
| C | GLN203 |
| C | ARG205 |
| C | A5P282 |
| C | NO3284 |
| C | HOH359 |
| C | HOH373 |
| C | HOH389 |
| C | HOH416 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 284 |
| Chain | Residue |
| B | PRO113 |
| B | ALA114 |
| B | LYS136 |
| B | ARG166 |
| B | NO3283 |
| B | HOH323 |
| B | HOH355 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 283 |
| Chain | Residue |
| D | PRO113 |
| D | ALA114 |
| D | LYS136 |
| D | ARG166 |
| D | NO3282 |
| D | HOH328 |
| D | HOH374 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 285 |
| Chain | Residue |
| B | ASN13 |
| B | PHE182 |
| B | ARG183 |
| B | VAL194 |
| B | GLY230 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 286 |
| Chain | Residue |
| A | ASP173 |
| A | ASN174 |
| A | HOH287 |
| A | HOH293 |
