3TMQ
Crystal structure of a 2-dehydro-3-deoxyphosphooctonate aldolase from Burkholderia pseudomallei in complex with D-arabinose-5-phosphate
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
A | 0009058 | biological_process | biosynthetic process |
A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
B | 0009058 | biological_process | biosynthetic process |
B | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
C | 0005737 | cellular_component | cytoplasm |
C | 0005829 | cellular_component | cytosol |
C | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
C | 0009058 | biological_process | biosynthetic process |
C | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
C | 0016740 | molecular_function | transferase activity |
C | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
D | 0005737 | cellular_component | cytoplasm |
D | 0005829 | cellular_component | cytosol |
D | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
D | 0009058 | biological_process | biosynthetic process |
D | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
D | 0016740 | molecular_function | transferase activity |
D | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE A5P C 282 |
Chain | Residue |
A | ARG118 |
C | ALA211 |
C | SER212 |
C | ASP248 |
C | NO3283 |
C | NO3284 |
C | EDO287 |
C | HOH342 |
C | HOH371 |
C | ASN24 |
C | LYS58 |
C | ASN60 |
C | ARG61 |
C | SER62 |
C | HIS200 |
C | GLN203 |
C | ARG205 |
site_id | AC2 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE A5P A 282 |
Chain | Residue |
A | ASN24 |
A | LYS58 |
A | ASN60 |
A | ARG61 |
A | SER62 |
A | HIS200 |
A | GLN203 |
A | ARG205 |
A | ALA211 |
A | SER212 |
A | ASP248 |
A | NO3283 |
A | NO3284 |
A | HOH312 |
A | HOH317 |
A | HOH519 |
C | ARG118 |
site_id | AC3 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE NO3 A 283 |
Chain | Residue |
A | LYS53 |
A | SER55 |
A | LYS58 |
A | GLN111 |
A | LYS136 |
A | HIS200 |
A | PHE235 |
A | A5P282 |
A | NO3284 |
A | HOH319 |
site_id | AC4 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE NO3 A 284 |
Chain | Residue |
A | PRO113 |
A | ALA114 |
A | LYS136 |
A | ARG166 |
A | A5P282 |
A | NO3283 |
A | HOH313 |
A | HOH319 |
A | HOH356 |
site_id | AC5 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE NO3 C 283 |
Chain | Residue |
C | LYS53 |
C | SER55 |
C | LYS58 |
C | GLN111 |
C | LYS136 |
C | HIS200 |
C | PHE235 |
C | A5P282 |
C | NO3284 |
C | HOH306 |
site_id | AC6 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE NO3 C 284 |
Chain | Residue |
C | PRO113 |
C | ALA114 |
C | LYS136 |
C | ARG166 |
C | A5P282 |
C | NO3283 |
C | EDO287 |
C | HOH306 |
C | HOH312 |
C | HOH373 |
site_id | AC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE NO3 C 285 |
Chain | Residue |
C | ASN13 |
C | PHE182 |
C | ARG183 |
C | VAL194 |
C | GLY230 |
site_id | AC8 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE NO3 C 286 |
Chain | Residue |
C | ASP173 |
C | ASN174 |
C | GLN203 |
C | CYS204 |
C | HOH359 |
C | HOH389 |
C | HOH416 |
site_id | AC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE NO3 A 285 |
Chain | Residue |
A | ASN13 |
A | PHE182 |
A | ARG183 |
A | VAL194 |
A | GLY230 |
site_id | BC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE NO3 D 282 |
Chain | Residue |
D | LYS53 |
D | SER55 |
D | ASP93 |
D | GLN111 |
D | LYS136 |
D | HIS200 |
D | PHE235 |
D | EDO283 |
site_id | BC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE NO3 B 282 |
Chain | Residue |
B | SER169 |
B | PHE170 |
B | GLY171 |
B | HOH431 |
D | SER169 |
D | GLY171 |
A | PHE170 |
site_id | BC3 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE NO3 B 283 |
Chain | Residue |
B | LYS53 |
B | SER55 |
B | LYS58 |
B | ASP93 |
B | GLN111 |
B | LYS136 |
B | HIS200 |
B | PHE235 |
B | EDO284 |
site_id | BC4 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE EDO C 287 |
Chain | Residue |
A | ARG118 |
C | ARG166 |
C | GLN203 |
C | ARG205 |
C | A5P282 |
C | NO3284 |
C | HOH359 |
C | HOH373 |
C | HOH389 |
C | HOH416 |
site_id | BC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO B 284 |
Chain | Residue |
B | PRO113 |
B | ALA114 |
B | LYS136 |
B | ARG166 |
B | NO3283 |
B | HOH323 |
B | HOH355 |
site_id | BC6 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO D 283 |
Chain | Residue |
D | PRO113 |
D | ALA114 |
D | LYS136 |
D | ARG166 |
D | NO3282 |
D | HOH328 |
D | HOH374 |
site_id | BC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO B 285 |
Chain | Residue |
B | ASN13 |
B | PHE182 |
B | ARG183 |
B | VAL194 |
B | GLY230 |
site_id | BC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 286 |
Chain | Residue |
A | ASP173 |
A | ASN174 |
A | HOH287 |
A | HOH293 |