3TJZ

Crystal Structure of Arf1 Bound to the gamma/zeta-COP Core Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0003925	molecular_function	G protein activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006886	biological_process	intracellular protein transport
A	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
A	0006893	biological_process	Golgi to plasma membrane transport
A	0010636	biological_process	positive regulation of mitochondrial fusion
A	0016192	biological_process	vesicle-mediated transport
A	0016236	biological_process	macroautophagy
A	0019217	biological_process	regulation of fatty acid metabolic process
A	0044232	cellular_component	organelle membrane contact site
A	0048193	biological_process	Golgi vesicle transport
A	0090141	biological_process	positive regulation of mitochondrial fission
A	1903292	biological_process	protein localization to Golgi membrane
A	1903358	biological_process	regulation of Golgi organization
B	0006886	biological_process	intracellular protein transport
B	0016192	biological_process	vesicle-mediated transport
B	0030117	cellular_component	membrane coat
C	0006886	biological_process	intracellular protein transport
C	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
C	0016192	biological_process	vesicle-mediated transport
C	0030117	cellular_component	membrane coat
C	0030126	cellular_component	COPI vesicle coat
D	0003924	molecular_function	GTPase activity
D	0003925	molecular_function	G protein activity
D	0005515	molecular_function	protein binding
D	0005525	molecular_function	GTP binding
D	0005737	cellular_component	cytoplasm
D	0005794	cellular_component	Golgi apparatus
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006886	biological_process	intracellular protein transport
D	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
D	0006893	biological_process	Golgi to plasma membrane transport
D	0010636	biological_process	positive regulation of mitochondrial fusion
D	0016192	biological_process	vesicle-mediated transport
D	0016236	biological_process	macroautophagy
D	0019217	biological_process	regulation of fatty acid metabolic process
D	0044232	cellular_component	organelle membrane contact site
D	0048193	biological_process	Golgi vesicle transport
D	0090141	biological_process	positive regulation of mitochondrial fission
D	1903292	biological_process	protein localization to Golgi membrane
D	1903358	biological_process	regulation of Golgi organization
E	0006886	biological_process	intracellular protein transport
E	0016192	biological_process	vesicle-mediated transport
E	0030117	cellular_component	membrane coat
F	0006886	biological_process	intracellular protein transport
F	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
F	0016192	biological_process	vesicle-mediated transport
F	0030117	cellular_component	membrane coat
F	0030126	cellular_component	COPI vesicle coat

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GNP A 201

Chain	Residue
A	ASP26
A	GLY69
A	GLY70
A	ASN126
A	LYS127
A	ASP129
A	CYS159
A	ALA160
A	MG202
D	GNP201
A	GLY27
A	ALA28
A	GLY29
A	LYS30
A	THR31
A	THR32
A	THR45
A	THR48

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 202

Chain	Residue
A	THR31
A	THR48
A	ASP67
A	GNP201

---

site_id	AC3
Number of Residues	20
Details	BINDING SITE FOR RESIDUE GNP D 201

Chain	Residue
A	GNP201
D	ASP26
D	GLY27
D	ALA28
D	GLY29
D	LYS30
D	THR31
D	THR32
D	THR45
D	THR48
D	GLY69
D	GLY70
D	ASN126
D	LYS127
D	ASP129
D	LEU130
D	CYS159
D	ALA160
D	THR161
D	MG202

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 202

Chain	Residue
D	THR31
D	THR48
D	ASP67
D	GNP201

---

Functional Information from PROSITE/UniProt

site_id	PS00989
Number of Residues	11
Details	CLAT_ADAPTOR_S Clathrin adaptor complexes small chain signature. VVYKssidLYF

Chain	Residue	Details
C	VAL67-PHE77

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	26
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20601958","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	74
Details	Repeat: {"description":"HEAT 1"}

Chain

Residue

Details

---