3TI0
Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and ddGTP-dC in Closed Conformation
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0006260 | biological_process | DNA replication |
| A | 0006261 | biological_process | DNA-templated DNA replication |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| D | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| D | 0006260 | biological_process | DNA replication |
| D | 0006261 | biological_process | DNA-templated DNA replication |
| D | 0008408 | molecular_function | 3'-5' exonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE DG3 A 201 |
| Chain | Residue |
| A | MG1 |
| A | ARG702 |
| A | LYS706 |
| A | TYR710 |
| A | TYR714 |
| A | ASP830 |
| A | HOH1011 |
| A | HOH1070 |
| A | HOH1151 |
| A | HOH1288 |
| A | HOH1314 |
| A | ARG615 |
| A | HOH1354 |
| B | DDG29 |
| C | DC3 |
| C | DC4 |
| A | ASP653 |
| A | TYR654 |
| A | SER655 |
| A | GLN656 |
| A | ILE657 |
| A | GLU658 |
| A | HIS682 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 1 |
| Chain | Residue |
| A | DG3201 |
| A | ASP653 |
| A | TYR654 |
| A | ASP830 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2 |
| Chain | Residue |
| A | ARG517 |
| A | ASN573 |
| D | LYS730 |
| site_id | AC4 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE DG3 D 202 |
| Chain | Residue |
| D | MG2 |
| D | HOH42 |
| D | HOH107 |
| D | HOH238 |
| D | HOH254 |
| D | ARG615 |
| D | TYR654 |
| D | SER655 |
| D | GLN656 |
| D | ILE657 |
| D | GLU658 |
| D | HIS682 |
| D | ARG702 |
| D | LYS706 |
| D | TYR710 |
| D | TYR714 |
| D | ASP830 |
| D | HOH890 |
| D | HOH973 |
| D | HOH1117 |
| D | HOH1178 |
| D | HOH1686 |
| D | HOH1687 |
| E | DDG29 |
| F | DC3 |
| F | DC4 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG D 2 |
| Chain | Residue |
| D | DG3202 |
| D | TYR654 |
| D | ASP830 |
| D | HOH1687 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1 |
| Chain | Residue |
| D | MET299 |
| D | ALA300 |
| D | ARG343 |
| D | ARG677 |
| D | HOH1434 |
Functional Information from PROSITE/UniProt
| site_id | PS00447 |
| Number of Residues | 20 |
| Details | DNA_POLYMERASE_A DNA polymerase family A signature. RrqAKavnYGivYgiSdygL |
| Chain | Residue | Details |
| A | ARG702-LEU721 |
