3T6J
Structure of human DPPIII in complex with the opioid peptide Tynorphin, at 3.0 Angstroms
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006508 | biological_process | proteolysis |
| A | 0008235 | molecular_function | metalloexopeptidase activity |
| A | 0008239 | molecular_function | dipeptidyl-peptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR CHAIN B OF TYNORPHIN |
| Chain | Residue |
| A | GLU316 |
| A | ASN394 |
| A | GLN446 |
| A | VAL447 |
| A | HIS450 |
| A | HIS455 |
| A | GLU508 |
| A | GLU512 |
| A | HIS568 |
| A | ARG572 |
| A | ARG669 |
| A | TYR318 |
| A | ILE386 |
| A | PRO387 |
| A | ALA388 |
| A | GLY389 |
| A | ILE390 |
| A | ASN391 |
| A | ILE392 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"UniProtKB","id":"O55096","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22493238","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3FVY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
