3T59
C76A/C455S mutant of mouse QSOX1 containing an interdomain disulfide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016971 | molecular_function | flavin-dependent sulfhydryl oxidase activity |
| A | 0016972 | molecular_function | thiol oxidase activity |
| B | 0016971 | molecular_function | flavin-dependent sulfhydryl oxidase activity |
| B | 0016972 | molecular_function | thiol oxidase activity |
| C | 0016971 | molecular_function | flavin-dependent sulfhydryl oxidase activity |
| C | 0016972 | molecular_function | thiol oxidase activity |
| D | 0016971 | molecular_function | flavin-dependent sulfhydryl oxidase activity |
| D | 0016972 | molecular_function | thiol oxidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE FAD A 601 |
| Chain | Residue |
| A | GLY74 |
| A | TRP481 |
| A | HIS484 |
| A | ASN485 |
| A | ASN488 |
| A | ARG490 |
| A | LEU491 |
| A | LYS503 |
| A | TRP506 |
| A | PHE539 |
| A | HOH723 |
| A | ARG404 |
| A | HOH749 |
| A | PRO407 |
| A | CYS408 |
| A | LEU410 |
| A | TRP411 |
| A | HIS415 |
| A | SER455 |
| A | PHE459 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE FAD B 601 |
| Chain | Residue |
| B | GLY74 |
| B | ARG404 |
| B | PRO407 |
| B | CYS408 |
| B | TRP411 |
| B | VAL412 |
| B | HIS415 |
| B | SER455 |
| B | PHE459 |
| B | TRP481 |
| B | HIS484 |
| B | ASN485 |
| B | VAL487 |
| B | ASN488 |
| B | ARG490 |
| B | LEU491 |
| B | LYS503 |
| B | TRP506 |
| B | PHE539 |
| B | HOH710 |
| B | HOH711 |
| B | HOH723 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE FAD C 601 |
| Chain | Residue |
| C | GLY74 |
| C | ARG404 |
| C | PRO407 |
| C | CYS408 |
| C | TRP411 |
| C | HIS415 |
| C | SER455 |
| C | HIS458 |
| C | PHE459 |
| C | TRP481 |
| C | HIS484 |
| C | ASN485 |
| C | VAL487 |
| C | ASN488 |
| C | ARG490 |
| C | LEU491 |
| C | LYS503 |
| C | TRP506 |
| C | PHE539 |
| C | HOH702 |
| C | HOH741 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE FAD D 601 |
| Chain | Residue |
| D | GLY74 |
| D | ARG299 |
| D | ARG404 |
| D | PRO407 |
| D | CYS408 |
| D | LEU410 |
| D | TRP411 |
| D | HIS415 |
| D | SER455 |
| D | PHE459 |
| D | TRP481 |
| D | HIS484 |
| D | ASN485 |
| D | VAL487 |
| D | ASN488 |
| D | ARG490 |
| D | LEU491 |
| D | LYS503 |
| D | TRP506 |
| D | PHE539 |
| D | HOH720 |
| D | HOH721 |
| D | HOH726 |
| D | HOH737 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 428 |
| Details | Domain: {"description":"ERV/ALR sulfhydryl oxidase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00654","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 48 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22801504","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3T58","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3T59","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O00391","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
