3T3O

Molecular basis for the recognition and cleavage of RNA (CUGG) by the bifunctional 5'-3' exo/endoribonuclease RNase J

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004521	molecular_function	RNA endonuclease activity
A	0004527	molecular_function	exonuclease activity
A	0004534	molecular_function	5'-3' RNA exonuclease activity
A	0005737	cellular_component	cytoplasm
A	0006364	biological_process	rRNA processing
A	0006396	biological_process	RNA processing
A	0008270	molecular_function	zinc ion binding
A	0016787	molecular_function	hydrolase activity
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ZN A 600

Chain	Residue
A	HIS75
A	ASP79
A	HIS80
A	ASP172
A	HIS398
A	HOH570
B	OMC901

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GOL A 701

Chain	Residue
A	GLU442

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Functional Information from PROSITE/UniProt

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VIWAAEKYGRKvamegrS

Chain	Residue	Details
A	VAL250-SER267

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01491","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21893286","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"Substrate binding"}

Chain

Residue

Details

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