3T36

Crystal structure of lytic transglycosylase MltE from Eschericha coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000270	biological_process	peptidoglycan metabolic process
A	0008932	molecular_function	lytic endotransglycosylase activity
A	0008933	molecular_function	lytic transglycosylase activity
A	0009279	cellular_component	cell outer membrane
A	0016020	cellular_component	membrane
A	0016829	molecular_function	lyase activity
A	0016837	molecular_function	carbon-oxygen lyase activity, acting on polysaccharides
A	0016998	biological_process	cell wall macromolecule catabolic process
A	0071555	biological_process	cell wall organization
B	0000270	biological_process	peptidoglycan metabolic process
B	0008932	molecular_function	lytic endotransglycosylase activity
B	0008933	molecular_function	lytic transglycosylase activity
B	0009279	cellular_component	cell outer membrane
B	0016020	cellular_component	membrane
B	0016829	molecular_function	lyase activity
B	0016837	molecular_function	carbon-oxygen lyase activity, acting on polysaccharides
B	0016998	biological_process	cell wall macromolecule catabolic process
B	0071555	biological_process	cell wall organization
C	0000270	biological_process	peptidoglycan metabolic process
C	0008932	molecular_function	lytic endotransglycosylase activity
C	0008933	molecular_function	lytic transglycosylase activity
C	0009279	cellular_component	cell outer membrane
C	0016020	cellular_component	membrane
C	0016829	molecular_function	lyase activity
C	0016837	molecular_function	carbon-oxygen lyase activity, acting on polysaccharides
C	0016998	biological_process	cell wall macromolecule catabolic process
C	0071555	biological_process	cell wall organization
D	0000270	biological_process	peptidoglycan metabolic process
D	0008932	molecular_function	lytic endotransglycosylase activity
D	0008933	molecular_function	lytic transglycosylase activity
D	0009279	cellular_component	cell outer membrane
D	0016020	cellular_component	membrane
D	0016829	molecular_function	lyase activity
D	0016837	molecular_function	carbon-oxygen lyase activity, acting on polysaccharides
D	0016998	biological_process	cell wall macromolecule catabolic process
D	0071555	biological_process	cell wall organization
E	0000270	biological_process	peptidoglycan metabolic process
E	0008932	molecular_function	lytic endotransglycosylase activity
E	0008933	molecular_function	lytic transglycosylase activity
E	0009279	cellular_component	cell outer membrane
E	0016020	cellular_component	membrane
E	0016829	molecular_function	lyase activity
E	0016837	molecular_function	carbon-oxygen lyase activity, acting on polysaccharides
E	0016998	biological_process	cell wall macromolecule catabolic process
E	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 204

Chain	Residue
A	ARG191
A	LYS195

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 204

Chain	Residue
B	TYR194
B	GLN198
B	HOH276
C	ARG155
C	HOH233
C	HOH348

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site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 E 204

Chain	Residue
B	HOH245
B	HOH283
E	TYR194
E	GLN198
E	HOH249
E	HOH293
B	ARG155

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Functional Information from PROSITE/UniProt

site_id	PS00922
Number of Residues	29
Details	TRANSGLYCOSYLASE Prokaryotic transglycosylases signature. IiaiESggnPnavSksnaiGLMqLkastS

Chain	Residue	Details
A	ILE60-SER88

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