3T1E

The structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a 4-helix bundle stalk

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004308	molecular_function	exo-alpha-sialidase activity
A	0016787	molecular_function	hydrolase activity
A	0019031	cellular_component	viral envelope
A	0019058	biological_process	viral life cycle
A	0019062	biological_process	virion attachment to host cell
A	0020002	cellular_component	host cell plasma membrane
A	0042802	molecular_function	identical protein binding
A	0044423	cellular_component	virion component
A	0046718	biological_process	symbiont entry into host cell
A	0046789	molecular_function	host cell surface receptor binding
A	0055036	cellular_component	virion membrane
B	0004308	molecular_function	exo-alpha-sialidase activity
B	0016787	molecular_function	hydrolase activity
B	0019031	cellular_component	viral envelope
B	0019058	biological_process	viral life cycle
B	0019062	biological_process	virion attachment to host cell
B	0020002	cellular_component	host cell plasma membrane
B	0042802	molecular_function	identical protein binding
B	0044423	cellular_component	virion component
B	0046718	biological_process	symbiont entry into host cell
B	0046789	molecular_function	host cell surface receptor binding
B	0055036	cellular_component	virion membrane
E	0004308	molecular_function	exo-alpha-sialidase activity
E	0016787	molecular_function	hydrolase activity
E	0019031	cellular_component	viral envelope
E	0019058	biological_process	viral life cycle
E	0019062	biological_process	virion attachment to host cell
E	0020002	cellular_component	host cell plasma membrane
E	0042802	molecular_function	identical protein binding
E	0044423	cellular_component	virion component
E	0046718	biological_process	symbiont entry into host cell
E	0046789	molecular_function	host cell surface receptor binding
E	0055036	cellular_component	virion membrane
F	0004308	molecular_function	exo-alpha-sialidase activity
F	0016787	molecular_function	hydrolase activity
F	0019031	cellular_component	viral envelope
F	0019058	biological_process	viral life cycle
F	0019062	biological_process	virion attachment to host cell
F	0020002	cellular_component	host cell plasma membrane
F	0042802	molecular_function	identical protein binding
F	0044423	cellular_component	virion component
F	0046718	biological_process	symbiont entry into host cell
F	0046789	molecular_function	host cell surface receptor binding
F	0055036	cellular_component	virion membrane

Functional Information from PROSITE/UniProt

site_id	PS00134
Number of Residues	6
Details	TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. MSATHC

Chain	Residue	Details
A	MET180-CYS185

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	Region: {"description":"Important for interaction with fusion/F protein","evidences":[{"source":"UniProtKB","id":"Q91UL0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	10
Details	Region: {"description":"Involved in neuraminidase activity","evidences":[{"source":"UniProtKB","id":"Q91UL0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"UniProtKB","id":"Q91UL0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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