3T12
MglA in complex with MglB in transition state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| B | 0032008 | biological_process | positive regulation of TOR signaling |
| B | 0060090 | molecular_function | molecular adaptor activity |
| C | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| C | 0032008 | biological_process | positive regulation of TOR signaling |
| C | 0060090 | molecular_function | molecular adaptor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE GDP A 197 |
| Chain | Residue |
| A | LEU22 |
| A | VAL170 |
| A | ALA171 |
| A | THR172 |
| A | MG198 |
| A | ALF200 |
| A | HOH203 |
| A | HOH222 |
| A | HOH240 |
| A | HOH280 |
| A | SER23 |
| A | GLY24 |
| A | LYS25 |
| A | THR26 |
| A | THR27 |
| A | ASN141 |
| A | LYS142 |
| A | ASP144 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 198 |
| Chain | Residue |
| A | THR26 |
| A | THR54 |
| A | GDP197 |
| A | ALF200 |
| A | HOH222 |
| A | HOH240 |
| A | HOH256 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 199 |
| Chain | Residue |
| A | ARG118 |
| B | MG1 |
| B | LYS45 |
| B | GLU46 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ALF A 200 |
| Chain | Residue |
| A | GLY21 |
| A | LEU22 |
| A | LYS25 |
| A | ARG53 |
| A | THR54 |
| A | VAL79 |
| A | PRO80 |
| A | GLY81 |
| A | GLN82 |
| A | GDP197 |
| A | MG198 |
| A | HOH203 |
| A | HOH209 |
| A | HOH222 |
| A | HOH239 |
| A | HOH240 |
| A | HOH256 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG B 1 |
| Chain | Residue |
| A | ARG118 |
| A | MG199 |
| B | GLU46 |
