3T0O

Crystal Structure Analysis of Human RNase T2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002376	biological_process	immune system process
A	0003723	molecular_function	RNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004521	molecular_function	RNA endonuclease activity
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005758	cellular_component	mitochondrial intermembrane space
A	0005764	cellular_component	lysosome
A	0005788	cellular_component	endoplasmic reticulum lumen
A	0006401	biological_process	RNA catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016829	molecular_function	lyase activity
A	0033897	molecular_function	ribonuclease T2 activity
A	0035578	cellular_component	azurophil granule lumen
A	0043202	cellular_component	lysosomal lumen
A	0045087	biological_process	innate immune response
A	0070062	cellular_component	extracellular exosome

Functional Information from PROSITE/UniProt

site_id	PS00530
Number of Residues	8
Details	RNASE_T2_1 Ribonuclease T2 family histidine active site 1. WtIHGLWP

Chain	Residue	Details
A	TRP62-PRO69

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site_id	PS00531
Number of Residues	12
Details	RNASE_T2_2 Ribonuclease T2 family histidine active site 2. FwkHEWeKHGtC

Chain	Residue	Details
A	PHE110-CYS121

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10045","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"evidences":[{"source":"UniProtKB","id":"P08056","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10046","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22735700","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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