3SZQ
Structure of an S. pombe APTX/DNA/AMP/Zn complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE AMP A 1 |
| Chain | Residue |
| A | HOH19 |
| A | PRO141 |
| A | SER142 |
| A | MET143 |
| A | HIS147 |
| A | HIS149 |
| A | HOH246 |
| A | HOH316 |
| B | DC1 |
| A | LEU38 |
| A | TYR41 |
| A | ASP63 |
| A | MET64 |
| A | PHE65 |
| A | LYS67 |
| A | HIS71 |
| A | HIS138 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BME A 2 |
| Chain | Residue |
| A | LYS134 |
| A | VAL135 |
| A | LYS176 |
| A | ASP178 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BME A 3 |
| Chain | Residue |
| A | SER142 |
| A | HOH316 |
| B | DC1 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 4 |
| Chain | Residue |
| A | CYS200 |
| A | CYS203 |
| A | HIS217 |
| A | GLU221 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile => ECO:0000305|PubMed:21984210, ECO:0000305|PubMed:26007660 |
| Chain | Residue | Details |
| A | HIS147 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21984210, ECO:0000269|PubMed:26007660, ECO:0007744|PDB:3SPD, ECO:0007744|PDB:3SPL, ECO:0007744|PDB:4XBA |
| Chain | Residue | Details |
| A | CYS200 | |
| A | CYS203 | |
| A | HIS217 | |
| A | GLU221 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Interaction with DNA => ECO:0000269|PubMed:21984210, ECO:0000269|PubMed:26007660 |
| Chain | Residue | Details |
| A | TYR41 |
