3SZQ
Structure of an S. pombe APTX/DNA/AMP/Zn complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE AMP A 1 |
| Chain | Residue |
| A | HOH19 |
| A | PRO141 |
| A | SER142 |
| A | MET143 |
| A | HIS147 |
| A | HIS149 |
| A | HOH246 |
| A | HOH316 |
| B | DC1 |
| A | LEU38 |
| A | TYR41 |
| A | ASP63 |
| A | MET64 |
| A | PHE65 |
| A | LYS67 |
| A | HIS71 |
| A | HIS138 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BME A 2 |
| Chain | Residue |
| A | LYS134 |
| A | VAL135 |
| A | LYS176 |
| A | ASP178 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BME A 3 |
| Chain | Residue |
| A | SER142 |
| A | HOH316 |
| B | DC1 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 4 |
| Chain | Residue |
| A | CYS200 |
| A | CYS203 |
| A | HIS217 |
| A | GLU221 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 122 |
| Details | Domain: {"description":"HIT"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Region: {"description":"Interaction with DNA","evidences":[{"source":"PubMed","id":"21984208","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21984210","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26007660","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"21984210","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"26007660","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21984210","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26007660","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3SPD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SPL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XBA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with DNA","evidences":[{"source":"PubMed","id":"21984210","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26007660","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
