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3SZ2

Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in an open binary complex with dG as templating nucleobase

Functional Information from GO Data
ChainGOidnamespacecontents
A0001882molecular_functionnucleoside binding
A0003676molecular_functionnucleic acid binding
A0003677molecular_functionDNA binding
A0003887molecular_functionDNA-directed DNA polymerase activity
A0006260biological_processDNA replication
A0006261biological_processDNA-templated DNA replication
A0006281biological_processDNA repair
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE FMT A 1
ChainResidue
AGLU462
AARG593
AGLU825

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE FMT A 833
ChainResidue
ASER739
AGLU742
AARG746

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE FMT A 834
ChainResidue
AASN583
DDC209
DFMT219
ATYR545
APRO579
AASN580

site_idAC4
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG B 1
ChainResidue
BHOH2
BHOH3
BHOH4
BHOH5
BHOH114
DHOH6

site_idAC5
Number of Residues5
DetailsBINDING SITE FOR RESIDUE GOL D 1
ChainResidue
AHOH198
DHOH148
DDC209
DDC210
DHOH256

site_idAC6
Number of Residues7
DetailsBINDING SITE FOR RESIDUE FMT D 217
ChainResidue
AHOH135
AASN485
AARG487
BHOH221
DHOH63
DDG211
DDT212

site_idAC7
Number of Residues4
DetailsBINDING SITE FOR RESIDUE FMT D 218
ChainResidue
DHOH193
DDC205
DDG206
DHOH220

site_idAC8
Number of Residues5
DetailsBINDING SITE FOR RESIDUE FMT D 219
ChainResidue
ATHR544
APRO579
AFMT834
DDC209
DDC210

Functional Information from PROSITE/UniProt
site_idPS00447
Number of Residues20
DetailsDNA_POLYMERASE_A DNA polymerase family A signature. RraAKtinFGvlYgmSahrL
ChainResidueDetails
AARG659-LEU678

226707

PDB entries from 2024-10-30

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