Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3SYN

Crystal structure of FlhF in complex with its activator

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
A	0006614	biological_process	SRP-dependent cotranslational protein targeting to membrane
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding
B	0006614	biological_process	SRP-dependent cotranslational protein targeting to membrane
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
C	0006614	biological_process	SRP-dependent cotranslational protein targeting to membrane
D	0003924	molecular_function	GTPase activity
D	0005525	molecular_function	GTP binding
D	0006614	biological_process	SRP-dependent cotranslational protein targeting to membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	BINDING SITE FOR RESIDUE GDP A 1

Chain	Residue
A	HOH9
A	LYS318
A	ASP320
A	GLU321
A	THR343
A	ASN344
A	GLY345
A	GLN346
A	MG367
A	AF3368
B	THR184
A	HOH38
B	AF3368
E	GLN8
A	GLY185
A	ALA186
A	GLY187
A	LYS188
A	THR189
A	THR190
A	GLN222

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 367

Chain	Residue
A	GDP1
A	HOH9
A	THR189
A	ASP213
A	AF3368
A	HOH373

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE AF3 A 368

Chain	Residue
A	GDP1
A	THR184
A	GLY185
A	LYS188
A	ASP213
A	ARG216
A	GLY262
A	MG367
A	HOH373
B	GDP2

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 3

Chain	Residue
A	ARG263
A	ASN264
A	TYR270
B	GDP2
B	HOH70
B	ASP320
B	GLN346

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 5

Chain	Residue
A	HOH24
A	LYS295
A	TYR296
A	SER327
B	SO48
B	LYS295

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 7

Chain	Residue
A	SER356
A	GLY359

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 10

Chain	Residue
A	CYS160
A	ALA166
A	SER356
A	PRO357
A	LEU358
B	GLU202
B	HIS204

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 13

Chain	Residue
A	LYS247
A	SER282
A	SER283

site_id	AC9
Number of Residues	24
Details	BINDING SITE FOR RESIDUE GDP B 2

Chain	Residue
A	SO43
A	THR184
A	AF3368
B	HOH12
B	HOH29
B	GLY185
B	ALA186
B	GLY187
B	LYS188
B	THR189
B	THR190
B	ARG216
B	GLN222
B	LYS318
B	ASP320
B	GLU321
B	THR343
B	ASN344
B	GLY345
B	GLN346
B	MG367
B	AF3368
B	HOH373
F	GLN8

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG B 367

Chain	Residue
B	GDP2
B	HOH29
B	THR189
B	ASP213
B	AF3368
B	HOH373
B	HOH374

site_id	BC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE AF3 B 368

Chain	Residue
B	ASP213
B	ARG216
B	GLY262
B	MG367
A	GDP1
B	GDP2
B	HOH29
B	HOH46
B	GLY185
B	LYS188

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 1

Chain	Residue
A	GLN346
B	HOH63
B	ARG263
B	ASN264
B	TYR270

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 8

Chain	Residue
A	SO45
A	LYS295
B	LYS295
B	TYR296
B	SER327

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 14

Chain	Residue
B	TYR177
B	LYS247
B	SER282
B	SER283

site_id	BC6
Number of Residues	23
Details	BINDING SITE FOR RESIDUE GDP C 3

Chain	Residue
C	HOH22
C	HOH57
C	GLY185
C	ALA186
C	GLY187
C	LYS188
C	THR189
C	THR190
C	GLN222
C	LYS318
C	ASP320
C	GLU321
C	THR343
C	ASN344
C	GLY345
C	GLN346
C	MG367
C	AF3368
C	HOH372
C	HOH373
D	THR184
D	AF3368
G	GLN8

site_id	BC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG C 367

Chain	Residue
C	GDP3
C	THR189
C	ASP213
C	ASP259
C	AF3368
C	HOH372
C	HOH373

site_id	BC8
Number of Residues	12
Details	BINDING SITE FOR RESIDUE AF3 C 368

Chain	Residue
C	GDP3
C	THR184
C	GLY185
C	LYS188
C	ASP213
C	ARG216
C	GLY262
C	MG367
C	HOH372
C	HOH373
D	GDP4
D	HOH33

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 4

Chain	Residue
C	ARG263
C	ASN264
C	TYR270
D	ASP320
D	GLN346

site_id	CC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 C 9

Chain	Residue
C	HOH41
C	ALA294
C	LYS295
C	TYR296
C	SER327
D	SO46
D	LYS295

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 11

Chain	Residue
A	HIS204
C	HIS174
C	SER175
C	SER283

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 15

Chain	Residue
C	TYR177
C	LYS247
C	SER282
C	SER283

site_id	CC4
Number of Residues	21
Details	BINDING SITE FOR RESIDUE GDP D 4

Chain	Residue
C	THR184
C	AF3368
D	HOH26
D	HOH40
D	GLY185
D	GLY187
D	LYS188
D	THR189
D	THR190
D	GLN222
D	LYS318
D	ASP320
D	GLU321
D	THR343
D	ASN344
D	GLY345
D	GLN346
D	MG367
D	AF3368
D	HOH373
H	GLN8

site_id	CC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 367

Chain	Residue
D	GDP4
D	HOH26
D	HOH40
D	THR189
D	ASP213
D	AF3368

site_id	CC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE AF3 D 368

Chain	Residue
C	GDP3
D	GDP4
D	HOH26
D	LYS188
D	ARG216
D	GLY262
D	MG367
D	HOH372

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 2

Chain	Residue
C	GLN346
D	ARG263
D	ASN264
D	TYR270

site_id	CC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 D 6

Chain	Residue
C	SO49
C	LYS295
D	HOH58
D	ALA294
D	LYS295
D	TYR296
D	SER327

site_id	CC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 12

Chain	Residue
C	SER356
C	GLY359

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	GLY182
D	GLY182
D	ASP259
D	THR317
A	ASP259
A	THR317
B	GLY182
B	ASP259
B	THR317
C	GLY182
C	ASP259
C	THR317

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)