Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005242 | molecular_function | inward rectifier potassium channel activity |
| A | 0006813 | biological_process | potassium ion transport |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA A 600 |
| Chain | Residue |
| A | ASP228 |
| A | ARG230 |
| A | SER232 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PIO A 400 |
| Chain | Residue |
| A | LYS199 |
| A | LYS200 |
| A | LYS64 |
| A | LYS90 |
| A | TRP91 |
| A | ARG92 |
| A | LYS194 |
| A | GLN197 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE K A 501 |
| Chain | Residue |
| A | GLY156 |
| A | GLY156 |
| A | GLY156 |
| A | GLY156 |
| A | K502 |
| A | K502 |
| A | K502 |
| A | K502 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE K A 502 |
| Chain | Residue |
| A | ILE155 |
| A | ILE155 |
| A | ILE155 |
| A | ILE155 |
| A | GLY156 |
| A | GLY156 |
| A | GLY156 |
| A | GLY156 |
| A | K501 |
| A | K501 |
| A | K501 |
| A | K501 |
| A | K503 |
| A | K503 |
| A | K503 |
| A | K503 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE K A 503 |
| Chain | Residue |
| A | THR154 |
| A | THR154 |
| A | THR154 |
| A | THR154 |
| A | ILE155 |
| A | ILE155 |
| A | ILE155 |
| A | ILE155 |
| A | K502 |
| A | K502 |
| A | K502 |
| A | K502 |
| A | K504 |
| A | K504 |
| A | K504 |
| A | K504 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE K A 504 |
| Chain | Residue |
| A | THR154 |
| A | THR154 |
| A | THR154 |
| A | THR154 |
| A | K503 |
| A | K503 |
| A | K503 |
| A | K503 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | TRANSMEM: Helical; Name=M1 => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG92-ILE116 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 31 |
| Details | TOPO_DOM: Extracellular => ECO:0000250 |
| Chain | Residue | Details |
| A | ALA117-GLY140 | |
| A | ARG160-GLU168 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 11 |
| Details | INTRAMEM: Helical; Pore-forming; Name=H5 => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE141-GLU152 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | INTRAMEM: Pore-forming => ECO:0000250 |
| Chain | Residue | Details |
| A | THR153-TYR159 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=M2 => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY169-CYS190 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | SITE: Role in the control of polyamine-mediated channel gating and in the blocking by intracellular magnesium => ECO:0000250 |
| Chain | Residue | Details |
| A | ASN184 | |
