3SXN
Mycobacterium tuberculosis Eis protein initiates modulation of host immune responses by acetylation of DUSP16/MKP-7
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008080 | molecular_function | N-acetyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| A | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| B | 0008080 | molecular_function | N-acetyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| B | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| C | 0008080 | molecular_function | N-acetyltransferase activity |
| C | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| C | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| C | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| D | 0008080 | molecular_function | N-acetyltransferase activity |
| D | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| D | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| D | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| E | 0008080 | molecular_function | N-acetyltransferase activity |
| E | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| E | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| E | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| F | 0008080 | molecular_function | N-acetyltransferase activity |
| F | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| F | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| F | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE COA A 500 |
| Chain | Residue |
| A | PHE26 |
| A | LEU97 |
| A | ARG98 |
| A | THR119 |
| A | SER121 |
| A | GLU122 |
| A | GLY124 |
| A | ILE125 |
| A | TYR126 |
| A | ARG128 |
| A | HOH676 |
| A | VAL85 |
| A | HOH685 |
| A | HOH689 |
| A | HOH773 |
| A | HOH894 |
| A | HOH900 |
| F | ASP258 |
| A | ALA86 |
| A | VAL87 |
| A | ARG92 |
| A | ARG93 |
| A | ARG94 |
| A | GLY95 |
| A | VAL96 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE COA B 500 |
| Chain | Residue |
| B | PHE26 |
| B | VAL85 |
| B | ALA86 |
| B | VAL87 |
| B | ARG92 |
| B | ARG93 |
| B | ARG94 |
| B | GLY95 |
| B | VAL96 |
| B | LEU97 |
| B | ARG98 |
| B | THR119 |
| B | SER121 |
| B | GLU122 |
| B | GLY124 |
| B | ILE125 |
| B | TYR126 |
| B | ARG128 |
| B | HOH614 |
| B | HOH766 |
| B | HOH830 |
| B | HOH856 |
| B | HOH919 |
| B | HOH978 |
| D | ASP258 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE COA C 500 |
| Chain | Residue |
| A | ASP258 |
| C | PHE26 |
| C | VAL85 |
| C | ALA86 |
| C | VAL87 |
| C | ARG92 |
| C | ARG93 |
| C | ARG94 |
| C | GLY95 |
| C | VAL96 |
| C | LEU97 |
| C | ARG98 |
| C | THR119 |
| C | SER121 |
| C | GLU122 |
| C | GLY124 |
| C | ILE125 |
| C | TYR126 |
| C | ARG128 |
| C | HOH645 |
| C | HOH689 |
| C | HOH816 |
| C | HOH839 |
| C | HOH855 |
| C | HOH861 |
| site_id | AC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE COA D 500 |
| Chain | Residue |
| D | ALA25 |
| D | PHE26 |
| D | VAL85 |
| D | ALA86 |
| D | VAL87 |
| D | ARG92 |
| D | ARG93 |
| D | ARG94 |
| D | GLY95 |
| D | VAL96 |
| D | LEU97 |
| D | ARG98 |
| D | THR119 |
| D | SER121 |
| D | GLU122 |
| D | GLY124 |
| D | ILE125 |
| D | TYR126 |
| D | ARG128 |
| D | HOH809 |
| D | HOH850 |
| D | HOH918 |
| E | ASP258 |
| site_id | AC5 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE COA E 500 |
| Chain | Residue |
| E | PHE26 |
| E | VAL85 |
| E | VAL87 |
| E | ARG92 |
| E | ARG93 |
| E | ARG94 |
| E | GLY95 |
| E | VAL96 |
| E | LEU97 |
| E | ARG98 |
| E | THR119 |
| E | SER121 |
| E | GLU122 |
| E | GLY124 |
| E | ILE125 |
| E | TYR126 |
| E | ARG128 |
| E | HOH782 |
| E | HOH800 |
| E | HOH815 |
| B | ASP258 |
| site_id | AC6 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE COA F 500 |
| Chain | Residue |
| C | ASP258 |
| F | PHE26 |
| F | VAL85 |
| F | ALA86 |
| F | VAL87 |
| F | ARG92 |
| F | ARG93 |
| F | ARG94 |
| F | GLY95 |
| F | VAL96 |
| F | LEU97 |
| F | ARG98 |
| F | SER121 |
| F | GLU122 |
| F | GLY124 |
| F | ILE125 |
| F | TYR126 |
| F | ARG128 |
| F | HOH654 |
| F | HOH772 |
