Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001882 | molecular_function | nucleoside binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0006260 | biological_process | DNA replication |
| A | 0006261 | biological_process | DNA-templated DNA replication |
| A | 0006281 | biological_process | DNA repair |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE 5SI A 1 |
| Chain | Residue |
| A | HOH153 |
| A | PRO816 |
| A | MG834 |
| A | MG842 |
| A | HOH901 |
| A | HOH905 |
| A | HOH906 |
| A | HOH154 |
| A | HOH170 |
| A | GLN633 |
| A | ARG801 |
| A | LYS804 |
| A | GLU805 |
| A | LEU813 |
| A | ALA814 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 5SI A 833 |
| Chain | Residue |
| A | HOH169 |
| A | HOH191 |
| A | ARG573 |
| A | ASP610 |
| A | TYR611 |
| A | GLN613 |
| A | ILE614 |
| A | GLU615 |
| A | HIS639 |
| A | ARG659 |
| A | LYS663 |
| A | THR664 |
| A | PHE667 |
| A | ASP785 |
| A | MG836 |
| A | MG837 |
| A | HOH893 |
| B | HOH49 |
| B | DOC112 |
| C | DG205 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 834 |
| Chain | Residue |
| A | 5SI1 |
| A | HOH153 |
| A | HOH154 |
| A | HOH170 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 835 |
| Chain | Residue |
| A | THR544 |
| A | TYR545 |
| A | PRO579 |
| A | ASN580 |
| A | ASN583 |
| A | HOH871 |
| A | HOH882 |
| C | HOH95 |
| C | DC209 |
| C | DC210 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 2 |
| Chain | Residue |
| A | HOH155 |
| A | ARG313 |
| A | TRP318 |
| A | ASP551 |
| A | LEU552 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A 8 |
| Chain | Residue |
| A | GLU337 |
| A | LYS340 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A 9 |
| Chain | Residue |
| A | HIS443 |
| A | THR447 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 836 |
| Chain | Residue |
| A | ASP610 |
| A | TYR611 |
| A | ASP785 |
| A | 5SI833 |
| A | MG837 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 837 |
| Chain | Residue |
| A | HOH163 |
| A | ASP610 |
| A | ASP785 |
| A | 5SI833 |
| A | MG836 |
| A | HOH855 |
| B | DOC112 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 838 |
| Chain | Residue |
| A | ILE823 |
| A | GLY824 |
| A | GLU825 |
| A | SER829 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 839 |
| Chain | Residue |
| A | PRO792 |
| A | LYS793 |
| A | GLU794 |
| A | ARG795 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT A 840 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT A 841 |
| Chain | Residue |
| A | LEU311 |
| A | GLU400 |
| A | ARG405 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 842 |
| Chain | Residue |
| A | 5SI1 |
| A | HOH901 |
| A | HOH902 |
| A | HOH903 |
| A | HOH904 |
| A | HOH905 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT A 843 |
| Chain | Residue |
| A | ASP488 |
| A | LYS511 |
| A | HOH852 |
| B | DC106 |
| C | DT212 |
| C | FMT217 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT A 844 |
| Chain | Residue |
| A | GLU708 |
| A | ARG715 |
| A | HOH908 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT A 845 |
| Chain | Residue |
| A | HOH106 |
| A | ASN485 |
| B | DG107 |
| A | HOH89 |
| A | HOH90 |
| site_id | BC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT A 846 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A 847 |
| Chain | Residue |
| A | TYR455 |
| A | ARG596 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 1 |
| Chain | Residue |
| B | HOH2 |
| B | HOH3 |
| B | HOH4 |
| B | HOH5 |
| B | HOH6 |
| C | HOH222 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 3 |
| Chain | Residue |
| C | HOH41 |
| C | DG205 |
| C | DG206 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT C 4 |
| Chain | Residue |
| A | ARG728 |
| C | DG206 |
| C | DC207 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT C 6 |
| Chain | Residue |
| C | HOH135 |
| C | DC207 |
| C | DG208 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT C 1 |
| Chain | Residue |
| C | HOH35 |
| C | DG213 |
| C | DG214 |
| site_id | CC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FMT C 217 |
| Chain | Residue |
| A | HOH90 |
| A | HOH121 |
| A | ARG487 |
| A | FMT843 |
| A | HOH852 |
| C | HOH8 |
| C | DG211 |
| C | DT212 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 218 |
| Chain | Residue |
| B | DC104 |
| C | HOH36 |
| C | DC210 |
| C | DG211 |
| C | DT212 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT C 219 |
| Chain | Residue |
| A | ARG556 |
| B | DC103 |
| C | DT215 |
| C | DC216 |
Functional Information from PROSITE/UniProt
| site_id | PS00447 |
| Number of Residues | 20 |
| Details | DNA_POLYMERASE_A DNA polymerase family A signature. RraAKtinFGvlYgmSahrL |
| Chain | Residue | Details |
| A | ARG659-LEU678 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 422 |
| Details | Region: {"description":"Polymerase","evidences":[{"evidenceCode":"ECO:0000250"}]} |
