Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3STA

Crystal structure of ClpP in tetradecameric form from Staphylococcus aureus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004176	molecular_function	ATP-dependent peptidase activity
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005737	cellular_component	cytoplasm
A	0006508	biological_process	proteolysis
A	0008236	molecular_function	serine-type peptidase activity
A	0042802	molecular_function	identical protein binding
B	0004176	molecular_function	ATP-dependent peptidase activity
B	0004252	molecular_function	serine-type endopeptidase activity
B	0005737	cellular_component	cytoplasm
B	0006508	biological_process	proteolysis
B	0008236	molecular_function	serine-type peptidase activity
B	0042802	molecular_function	identical protein binding
C	0004176	molecular_function	ATP-dependent peptidase activity
C	0004252	molecular_function	serine-type endopeptidase activity
C	0005737	cellular_component	cytoplasm
C	0006508	biological_process	proteolysis
C	0008236	molecular_function	serine-type peptidase activity
C	0042802	molecular_function	identical protein binding
E	0004176	molecular_function	ATP-dependent peptidase activity
E	0004252	molecular_function	serine-type endopeptidase activity
E	0005737	cellular_component	cytoplasm
E	0006508	biological_process	proteolysis
E	0008236	molecular_function	serine-type peptidase activity
E	0042802	molecular_function	identical protein binding
F	0004176	molecular_function	ATP-dependent peptidase activity
F	0004252	molecular_function	serine-type endopeptidase activity
F	0005737	cellular_component	cytoplasm
F	0006508	biological_process	proteolysis
F	0008236	molecular_function	serine-type peptidase activity
F	0042802	molecular_function	identical protein binding
G	0004176	molecular_function	ATP-dependent peptidase activity
G	0004252	molecular_function	serine-type endopeptidase activity
G	0005737	cellular_component	cytoplasm
G	0006508	biological_process	proteolysis
G	0008236	molecular_function	serine-type peptidase activity
G	0042802	molecular_function	identical protein binding
I	0004176	molecular_function	ATP-dependent peptidase activity
I	0004252	molecular_function	serine-type endopeptidase activity
I	0005737	cellular_component	cytoplasm
I	0006508	biological_process	proteolysis
I	0008236	molecular_function	serine-type peptidase activity
I	0042802	molecular_function	identical protein binding
K	0004176	molecular_function	ATP-dependent peptidase activity
K	0004252	molecular_function	serine-type endopeptidase activity
K	0005737	cellular_component	cytoplasm
K	0006508	biological_process	proteolysis
K	0008236	molecular_function	serine-type peptidase activity
K	0042802	molecular_function	identical protein binding
L	0004176	molecular_function	ATP-dependent peptidase activity
L	0004252	molecular_function	serine-type endopeptidase activity
L	0005737	cellular_component	cytoplasm
L	0006508	biological_process	proteolysis
L	0008236	molecular_function	serine-type peptidase activity
L	0042802	molecular_function	identical protein binding
M	0004176	molecular_function	ATP-dependent peptidase activity
M	0004252	molecular_function	serine-type endopeptidase activity
M	0005737	cellular_component	cytoplasm
M	0006508	biological_process	proteolysis
M	0008236	molecular_function	serine-type peptidase activity
M	0042802	molecular_function	identical protein binding
N	0004176	molecular_function	ATP-dependent peptidase activity
N	0004252	molecular_function	serine-type endopeptidase activity
N	0005737	cellular_component	cytoplasm
N	0006508	biological_process	proteolysis
N	0008236	molecular_function	serine-type peptidase activity
N	0042802	molecular_function	identical protein binding
S	0004176	molecular_function	ATP-dependent peptidase activity
S	0004252	molecular_function	serine-type endopeptidase activity
S	0005737	cellular_component	cytoplasm
S	0006508	biological_process	proteolysis
S	0008236	molecular_function	serine-type peptidase activity
S	0042802	molecular_function	identical protein binding
T	0004176	molecular_function	ATP-dependent peptidase activity
T	0004252	molecular_function	serine-type endopeptidase activity
T	0005737	cellular_component	cytoplasm
T	0006508	biological_process	proteolysis
T	0008236	molecular_function	serine-type peptidase activity
T	0042802	molecular_function	identical protein binding
V	0004176	molecular_function	ATP-dependent peptidase activity
V	0004252	molecular_function	serine-type endopeptidase activity
V	0005737	cellular_component	cytoplasm
V	0006508	biological_process	proteolysis
V	0008236	molecular_function	serine-type peptidase activity
V	0042802	molecular_function	identical protein binding

Functional Information from PROSITE/UniProt

site_id	PS00381
Number of Residues	12
Details	CLP_PROTEASE_SER Endopeptidase Clp serine active site. TicIGmAASMGS

Chain	Residue	Details
V	THR90-SER101

site_id	PS00382
Number of Residues	14
Details	CLP_PROTEASE_HIS Endopeptidase Clp histidine active site. RfalPnaeVMIHQP

Chain	Residue	Details
V	ARG112-PRO125

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	ACT_SITE: Nucleophile => ECO:0000255\|HAMAP-Rule:MF_00444

Chain	Residue	Details
V	SER98
L	SER98
M	SER98
N	SER98
S	SER98
T	SER98
A	SER98
B	SER98
C	SER98
E	SER98
F	SER98
G	SER98
I	SER98
K	SER98

site_id	SWS_FT_FI2
Number of Residues	14
Details	ACT_SITE: ACT_SITE => ECO:0000255\|HAMAP-Rule:MF_00444

Chain	Residue	Details
V	HIS123
L	HIS123
M	HIS123
N	HIS123
S	HIS123
T	HIS123
A	HIS123
B	HIS123
C	HIS123
E	HIS123
F	HIS123
G	HIS123
I	HIS123
K	HIS123

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)