3SO4

Methionine-adenosyltransferase from Entamoeba histolytica

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004478	molecular_function	methionine adenosyltransferase activity
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006556	biological_process	S-adenosylmethionine biosynthetic process
A	0006730	biological_process	one-carbon metabolic process
A	0016740	molecular_function	transferase activity
A	0046872	molecular_function	metal ion binding
B	0004478	molecular_function	methionine adenosyltransferase activity
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0006556	biological_process	S-adenosylmethionine biosynthetic process
B	0006730	biological_process	one-carbon metabolic process
B	0016740	molecular_function	transferase activity
B	0046872	molecular_function	metal ion binding
C	0004478	molecular_function	methionine adenosyltransferase activity
C	0005524	molecular_function	ATP binding
C	0005829	cellular_component	cytosol
C	0006556	biological_process	S-adenosylmethionine biosynthetic process
C	0006730	biological_process	one-carbon metabolic process
C	0016740	molecular_function	transferase activity
C	0046872	molecular_function	metal ion binding
D	0004478	molecular_function	methionine adenosyltransferase activity
D	0005524	molecular_function	ATP binding
D	0005829	cellular_component	cytosol
D	0006556	biological_process	S-adenosylmethionine biosynthetic process
D	0006730	biological_process	one-carbon metabolic process
D	0016740	molecular_function	transferase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A 400

Chain	Residue
A	ASP18
A	ARG251
A	LYS252
A	HOH401
B	LYS272
B	ASP278

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT B 400

Chain	Residue
B	LYS252
B	HOH401
A	LYS272
A	ASP278
B	ASP18

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT C 400

Chain	Residue
C	LYS252
C	HOH401
D	LYS272

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT D 400

Chain	Residue
C	LYS272
D	ASP18
D	ARG251
D	LYS252
D	HOH401

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Functional Information from PROSITE/UniProt

site_id	PS00376
Number of Residues	11
Details	ADOMET_SYNTHASE_1 S-adenosylmethionine synthase signature 1. GAGDQGimfGY

Chain	Residue	Details
A	GLY118-TYR128

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site_id	PS00377
Number of Residues	9
Details	ADOMET_SYNTHASE_2 S-adenosylmethionine synthase signature 2. GGGAFSgKD

Chain	Residue	Details
A	GLY265-ASP273

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