3SL1
Crystal Structure of P. falciparum arginase complexed with 2-amino-6-borono-2-methylhexanoic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000050 | biological_process | urea cycle |
| A | 0004053 | molecular_function | arginase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006525 | biological_process | arginine metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 412 |
| Chain | Residue |
| A | ASP216 |
| A | HIS218 |
| A | ASP323 |
| A | ASP325 |
| A | MN413 |
| A | FB6414 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN A 413 |
| Chain | Residue |
| A | ASP323 |
| A | MN412 |
| A | FB6414 |
| A | HOH593 |
| A | HIS193 |
| A | ASP216 |
| A | ASP220 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE FB6 A 414 |
| Chain | Residue |
| A | ASP216 |
| A | HIS218 |
| A | ASP220 |
| A | ASN222 |
| A | SER229 |
| A | HIS233 |
| A | GLY234 |
| A | ASP274 |
| A | ASP323 |
| A | ASP325 |
| A | HIS381 |
| A | MN412 |
| A | MN413 |
| A | HOH425 |
| A | HOH471 |
| A | HOH477 |
| A | HOH485 |
| A | HOH525 |
| A | HOH593 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20527960","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21728378","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3MMR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SL1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20527960","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"21728378","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3MMR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SL1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
