3SJC

Crystal structure of S.cerevisiae Get3 in the semi-open state in complex with Get1 cytosolic domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000750	biological_process	pheromone-dependent signal transduction involved in conjugation with cellular fusion
A	0005085	molecular_function	guanyl-nucleotide exchange factor activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005794	cellular_component	Golgi apparatus
A	0005829	cellular_component	cytosol
A	0006457	biological_process	protein folding
A	0006620	biological_process	post-translational protein targeting to endoplasmic reticulum membrane
A	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
A	0008270	molecular_function	zinc ion binding
A	0009408	biological_process	response to heat
A	0010038	biological_process	response to metal ion
A	0016192	biological_process	vesicle-mediated transport
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0034599	biological_process	cellular response to oxidative stress
A	0042802	molecular_function	identical protein binding
A	0043529	cellular_component	GET complex
A	0044183	molecular_function	protein folding chaperone
A	0045048	biological_process	protein insertion into ER membrane
A	0046685	biological_process	response to arsenic-containing substance
A	0046872	molecular_function	metal ion binding
A	0051082	molecular_function	unfolded protein binding
A	0071816	biological_process	tail-anchored membrane protein insertion into ER membrane
B	0000166	molecular_function	nucleotide binding
B	0000750	biological_process	pheromone-dependent signal transduction involved in conjugation with cellular fusion
B	0005085	molecular_function	guanyl-nucleotide exchange factor activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005783	cellular_component	endoplasmic reticulum
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005794	cellular_component	Golgi apparatus
B	0005829	cellular_component	cytosol
B	0006457	biological_process	protein folding
B	0006620	biological_process	post-translational protein targeting to endoplasmic reticulum membrane
B	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
B	0008270	molecular_function	zinc ion binding
B	0009408	biological_process	response to heat
B	0010038	biological_process	response to metal ion
B	0016192	biological_process	vesicle-mediated transport
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0034599	biological_process	cellular response to oxidative stress
B	0042802	molecular_function	identical protein binding
B	0043529	cellular_component	GET complex
B	0044183	molecular_function	protein folding chaperone
B	0045048	biological_process	protein insertion into ER membrane
B	0046685	biological_process	response to arsenic-containing substance
B	0046872	molecular_function	metal ion binding
B	0051082	molecular_function	unfolded protein binding
B	0071816	biological_process	tail-anchored membrane protein insertion into ER membrane
C	0071816	biological_process	tail-anchored membrane protein insertion into ER membrane
D	0071816	biological_process	tail-anchored membrane protein insertion into ER membrane
E	0000166	molecular_function	nucleotide binding
E	0000750	biological_process	pheromone-dependent signal transduction involved in conjugation with cellular fusion
E	0005085	molecular_function	guanyl-nucleotide exchange factor activity
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005783	cellular_component	endoplasmic reticulum
E	0005789	cellular_component	endoplasmic reticulum membrane
E	0005794	cellular_component	Golgi apparatus
E	0005829	cellular_component	cytosol
E	0006457	biological_process	protein folding
E	0006620	biological_process	post-translational protein targeting to endoplasmic reticulum membrane
E	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
E	0008270	molecular_function	zinc ion binding
E	0009408	biological_process	response to heat
E	0010038	biological_process	response to metal ion
E	0016192	biological_process	vesicle-mediated transport
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0034599	biological_process	cellular response to oxidative stress
E	0042802	molecular_function	identical protein binding
E	0043529	cellular_component	GET complex
E	0044183	molecular_function	protein folding chaperone
E	0045048	biological_process	protein insertion into ER membrane
E	0046685	biological_process	response to arsenic-containing substance
E	0046872	molecular_function	metal ion binding
E	0051082	molecular_function	unfolded protein binding
E	0071816	biological_process	tail-anchored membrane protein insertion into ER membrane
F	0000166	molecular_function	nucleotide binding
F	0000750	biological_process	pheromone-dependent signal transduction involved in conjugation with cellular fusion
F	0005085	molecular_function	guanyl-nucleotide exchange factor activity
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005783	cellular_component	endoplasmic reticulum
F	0005789	cellular_component	endoplasmic reticulum membrane
F	0005794	cellular_component	Golgi apparatus
F	0005829	cellular_component	cytosol
F	0006457	biological_process	protein folding
F	0006620	biological_process	post-translational protein targeting to endoplasmic reticulum membrane
F	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
F	0008270	molecular_function	zinc ion binding
F	0009408	biological_process	response to heat
F	0010038	biological_process	response to metal ion
F	0016192	biological_process	vesicle-mediated transport
F	0016787	molecular_function	hydrolase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0034599	biological_process	cellular response to oxidative stress
F	0042802	molecular_function	identical protein binding
F	0043529	cellular_component	GET complex
F	0044183	molecular_function	protein folding chaperone
F	0045048	biological_process	protein insertion into ER membrane
F	0046685	biological_process	response to arsenic-containing substance
F	0046872	molecular_function	metal ion binding
F	0051082	molecular_function	unfolded protein binding
F	0071816	biological_process	tail-anchored membrane protein insertion into ER membrane
G	0071816	biological_process	tail-anchored membrane protein insertion into ER membrane
H	0071816	biological_process	tail-anchored membrane protein insertion into ER membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 363

Chain	Residue
A	CYS285
A	CYS288
B	CYS285
B	CYS288

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 363

Chain	Residue
E	CYS285
E	CYS288
F	CYS285
F	CYS288

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	64
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03112","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19675567","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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