3SF6

Crystal structure of Glutaryl-CoA dehydrogenase from Mycobacterium smegmatis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000062	molecular_function	fatty-acyl-CoA binding
A	0004361	molecular_function	glutaryl-CoA dehydrogenase activity
A	0016491	molecular_function	oxidoreductase activity
A	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
A	0033539	biological_process	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A	0046949	biological_process	fatty-acyl-CoA biosynthetic process
A	0050660	molecular_function	flavin adenine dinucleotide binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	31
Details	BINDING SITE FOR RESIDUE FDA A 400

Chain	Residue
A	PHE144
A	ARG283
A	GLN285
A	PHE286
A	ILE290
A	PHE293
A	GLN294
A	THR351
A	VAL352
A	ALA355
A	SER373
A	LEU146
A	THR376
A	TYR377
A	THR380
A	GLU382
A	MET383
A	PHE398
A	HOH429
A	HOH431
A	HOH439
A	HOH446
A	THR147
A	HOH449
A	HOH684
A	GLY152
A	SER153
A	TRP177
A	ILE178
A	THR179
A	LEU220

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 410

Chain	Residue
A	THR36
A	GLY71
A	HOH420
A	HOH571

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 411

Chain	Residue
A	ARG192
A	GLY196
A	ILE197
A	SER246
A	LEU247
A	HOH668
A	HOH681

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 412

Chain	Residue
A	TYR90
A	VAL108
A	GLY112
A	SER113
A	HOH471

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 413

Chain	Residue
A	ASP17
A	ILE22
A	ARG34
A	GLU96
A	ARG270
A	TYR307
A	HOH529

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 414

Chain	Residue
A	GLY173
A	THR174
A	LEU230
A	ASP231
A	HOH649

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 415

Chain	Residue
A	GLU54
A	LYS215
A	SER216
A	ARG221
A	HOH555
A	HOH711

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 416

Chain	Residue
A	GLY396
A	ALA397
A	PHE398
A	ARG399

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 417

Chain	Residue
A	SER27
A	ALA28
A	ARG31
A	ARG234
A	HOH428
A	HOH541
A	HOH638

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