3SE2

Human poly(ADP-ribose) polymerase 14 (PARP14/ARTD8) - catalytic domain in complex with 6(5H)-phenanthridinone

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003950	molecular_function	NAD+-protein poly-ADP-ribosyltransferase activity
B	0003950	molecular_function	NAD+-protein poly-ADP-ribosyltransferase activity
C	0003950	molecular_function	NAD+-protein poly-ADP-ribosyltransferase activity
D	0003950	molecular_function	NAD+-protein poly-ADP-ribosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE LDR A 1

Chain	Residue
A	HIS1601
A	GLY1602
A	LYS1623
A	ASN1624
A	ALA1625
A	TYR1633
A	TYR1640
A	SER1641
A	TYR1646

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 1721

Chain	Residue
A	ASN1549
A	ALA1552
A	SER1553
A	ASN1556
D	ILE1675
D	VAL1676
D	PHE1705
D	TYR1706

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 3

Chain	Residue
A	ILE1570
A	ASN1572
A	PRO1573
A	TYR1711

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE LDR B 2

Chain	Residue
B	HIS1601
B	GLY1602
B	ALA1625
B	TYR1633
B	TYR1640
B	SER1641
B	TYR1646

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SCN B 5

Chain	Residue
B	GLN1534
B	ASN1614
B	ASN1617
B	TYR1708

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 3AB C 4

Chain	Residue
C	HOH130
C	HIS1601
C	GLY1602
C	TYR1633
C	ALA1635
C	SER1641
C	TYR1646

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL C 2

Chain	Residue
C	ASN1612

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL C 1721

Chain	Residue
C	ARG1569
C	ILE1570
C	GLN1571
C	ASN1572
C	TYR1711
C	GLU1713

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SCN C 7

Chain	Residue
B	LYS1582
B	TYR1706
B	ASP1707
C	PRO1543
C	SER1544

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 3AB D 3

Chain	Residue
D	HIS1601
D	GLY1602
D	TYR1633
D	SER1641
D	TYR1646
D	HOH1721

---

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 1

Chain	Residue
B	ASN1612

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL D 4

Chain	Residue
D	GLN1571
D	PRO1573
D	TRP1576
D	TYR1711

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SCN D 6

Chain	Residue
A	TYR1706
A	ASP1707
D	SER1544

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