Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3SBO

Structure of E.coli GDH from native source

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
A	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006520	biological_process	amino acid metabolic process
A	0006536	biological_process	glutamate metabolic process
A	0006537	biological_process	glutamate biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
A	0042802	molecular_function	identical protein binding
A	0097216	molecular_function	guanosine tetraphosphate binding
B	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
B	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006520	biological_process	amino acid metabolic process
B	0006536	biological_process	glutamate metabolic process
B	0006537	biological_process	glutamate biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
B	0042802	molecular_function	identical protein binding
B	0097216	molecular_function	guanosine tetraphosphate binding
C	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
C	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006520	biological_process	amino acid metabolic process
C	0006536	biological_process	glutamate metabolic process
C	0006537	biological_process	glutamate biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
C	0042802	molecular_function	identical protein binding
C	0097216	molecular_function	guanosine tetraphosphate binding
D	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
D	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006520	biological_process	amino acid metabolic process
D	0006536	biological_process	glutamate metabolic process
D	0006537	biological_process	glutamate biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
D	0042802	molecular_function	identical protein binding
D	0097216	molecular_function	guanosine tetraphosphate binding
E	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
E	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006520	biological_process	amino acid metabolic process
E	0006536	biological_process	glutamate metabolic process
E	0006537	biological_process	glutamate biosynthetic process
E	0016491	molecular_function	oxidoreductase activity
E	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
E	0042802	molecular_function	identical protein binding
E	0097216	molecular_function	guanosine tetraphosphate binding
F	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
F	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006520	biological_process	amino acid metabolic process
F	0006536	biological_process	glutamate metabolic process
F	0006537	biological_process	glutamate biosynthetic process
F	0016491	molecular_function	oxidoreductase activity
F	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
F	0042802	molecular_function	identical protein binding
F	0097216	molecular_function	guanosine tetraphosphate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 448

Chain	Residue
A	GLY167

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C 449

Chain	Residue
C	GLY167
C	GLY196

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL D 448

Chain	Residue
D	ASP134
D	LYS138

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL D 449

Chain	Residue
D	ALA160
D	ASP161
D	THR162

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL E 448

Chain	Residue
E	ASP134

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL E 449

Chain	Residue
E	GLY167

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL F 448

Chain	Residue
F	ASP134

Functional Information from PROSITE/UniProt

site_id	PS00074
Number of Residues	14
Details	GLFV_DEHYDROGENASE Glu / Leu / Phe / Val dehydrogenases active site. LpmGGGKgGsdfDP

Chain	Residue	Details
A	LEU122-PRO135

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10011","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details