3SBB

Disulphide-mediated Tetramer of T4 Lysozyme R76C/R80C by Synthetic Symmetrization

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0003796	molecular_function	lysozyme activity
C	0009253	biological_process	peptidoglycan catabolic process
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0016998	biological_process	cell wall macromolecule catabolic process
C	0030430	cellular_component	host cell cytoplasm
C	0031640	biological_process	killing of cells of another organism
C	0042742	biological_process	defense response to bacterium
C	0044659	biological_process	viral release from host cell by cytolysis

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL C 163

Chain	Residue
C	SER36
C	PHE114
C	ASN116
C	SER117
C	ASN132

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL C 164

Chain	Residue
C	HOH293
C	THR142
C	PRO143
C	ASN144
C	ARG145

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 165

Chain	Residue
C	ASP92
C	LYS124
C	TRP126

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098

Chain	Residue	Details
C	GLU11

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:1892846, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098

Chain	Residue	Details
C	ASP20

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:8266098

Chain	Residue	Details
C	LEU32
C	PHE104

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site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000303|PubMed:7831309

Chain	Residue	Details
C	SER117
C	ASN132

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	2
Details	M-CSA 921

Chain	Residue	Details
C	GLU11	proton shuttle (general acid/base)
C	ASP20	covalent catalysis

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