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3S9S

Ligand binding domain of PPARgamma complexed with a benzimidazole partial agonist

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues19
DetailsBINDING SITE FOR RESIDUE M0T A 1
ChainResidue
AHOH14
AILE326
ATYR327
ALEU330
AILE341
AMET348
APHE363
AMET364
AHIS449
ALEU465
ATYR473
AHOH22
AILE281
APHE282
AGLY284
ACYS285
AGLN286
ASER289
AHIS323

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
ChainResidueDetails
AGLN286
AHIS323
AHIS449
ATYR473

site_idSWS_FT_FI2
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649
ChainResidueDetails
ALYS224

222926

PDB entries from 2024-07-24

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