3S6B

Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum, PF10_0150

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006508	biological_process	proteolysis
A	0070006	molecular_function	metalloaminopeptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 369

Chain	Residue
A	PHE230
A	TYR255
A	LYS362
A	HOH450
A	HOH527

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE A 370

Chain	Residue
A	HOH385
A	HOH518
A	ASP204
A	HIS270
A	GLU303
A	GLU334

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 371

Chain	Residue
A	LYS121
A	ASP124
A	TYR125
A	THR351
A	ASP353
A	HOH530

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Functional Information from PROSITE/UniProt

site_id	PS00680
Number of Residues	19
Details	MAP_1 Methionine aminopeptidase subfamily 1 signature. YsGHGVGklfHsnptVp.HF

Chain	Residue	Details
A	TYR267-PHE285

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03174

Chain	Residue	Details
A	HIS176
A	ASP193
A	HIS277

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03174, ECO:0007744|PDB:3S6B

Chain	Residue	Details
A	ASP204
A	HIS270
A	GLU303
A	GLU334

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site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Important for substrate specificity to methionine => ECO:0000269|PubMed:27023914

Chain	Residue	Details
A	CYS167

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