Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 501 |
| Chain | Residue |
| A | ASN40 |
| A | ASN41 |
| A | PRO44 |
| A | HOH1054 |
| A | HOH1083 |
| B | ASN40 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 513 |
| Chain | Residue |
| A | ZN533 |
| A | HOH1080 |
| A | SER4 |
| A | LEU99 |
| A | IMD524 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE IMD A 524 |
| Chain | Residue |
| A | GLN2 |
| A | PHE3 |
| A | LEU99 |
| A | CL513 |
| A | ZN533 |
| B | PRO1 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE IMD A 526 |
| Chain | Residue |
| A | TYR14 |
| A | GLY17 |
| A | GLU65 |
| A | GLU65 |
| A | ZN536 |
| A | HOH1002 |
| A | HOH1002 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 533 |
| Chain | Residue |
| A | LYS7 |
| A | LEU99 |
| A | CL513 |
| A | IMD524 |
| A | HOH1080 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN A 535 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN A 536 |
| Chain | Residue |
| A | GLU65 |
| A | GLU65 |
| A | IMD526 |
| A | HOH1001 |
| A | HOH1001 |
| A | HOH1002 |
| A | HOH1002 |
| site_id | AC8 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE 478 B 201 |
| Chain | Residue |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP30 |
| A | ILE32 |
| A | GLY49 |
| A | ILE50 |
| A | ILE82 |
| A | ILE84 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | GLY48 |
| B | GLY49 |
| B | ILE50 |
| B | ILE84 |
| B | HOH1003 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL B 511 |
| Chain | Residue |
| B | VAL11 |
| B | THR12 |
| B | LYS45 |
| B | ILE46 |
| B | IMD523 |
| B | HOH1043 |
| B | HOH1073 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 512 |
| Chain | Residue |
| B | LYS7 |
| B | ASP30 |
| B | GLY48 |
| B | CL517 |
| B | IMD523 |
| B | ZN532 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 514 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 515 |
| Chain | Residue |
| B | SER4 |
| B | LEU5 |
| B | TRP6 |
| B | LYS7 |
| B | ZN534 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 516 |
| Chain | Residue |
| B | CL518 |
| B | IMD525 |
| B | ZN534 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 517 |
| Chain | Residue |
| B | ASP29 |
| B | ASP30 |
| B | CL512 |
| B | IMD523 |
| B | ZN532 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 518 |
| Chain | Residue |
| A | ARG8 |
| B | CL516 |
| B | ZN534 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE IMD B 521 |
| Chain | Residue |
| B | GLU21 |
| B | ILE46 |
| B | PHE53 |
| B | ASN55 |
| B | ASP79 |
| B | IMD522 |
| B | ZN531 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IMD B 522 |
| Chain | Residue |
| B | GLU21 |
| B | ASP79 |
| B | IMD521 |
| B | ZN531 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE IMD B 523 |
| Chain | Residue |
| B | ASP30 |
| B | ILE46 |
| B | MET76 |
| B | CL511 |
| B | CL512 |
| B | CL517 |
| B | ZN532 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE IMD B 525 |
| Chain | Residue |
| A | ARG8 |
| A | PRO81 |
| B | TRP6 |
| B | CL516 |
| B | ZN534 |
| B | HOH1051 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 531 |
| Chain | Residue |
| B | GLU21 |
| B | ASP79 |
| B | IMD521 |
| B | IMD522 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 532 |
| Chain | Residue |
| B | ASP30 |
| B | CL512 |
| B | CL517 |
| B | IMD523 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 534 |
| Chain | Residue |
| B | CL515 |
| B | CL516 |
| B | CL518 |
| B | IMD525 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 537 |
| Chain | Residue |
| B | GLU65 |
| B | CL514 |
| B | HOH1007 |
| B | HOH1013 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VLLDTGADDSIV |
| Chain | Residue | Details |
| A | VAL22-VAL33 | |
