Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0042802 | molecular_function | identical protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 478 A 401 |
| Chain | Residue |
| A | ASP25 |
| A | HOH1127 |
| A | HOH1128 |
| B | ASP125 |
| B | GLY127 |
| B | ALA128 |
| B | ASP129 |
| B | ASP130 |
| B | VAL147 |
| B | GLY148 |
| B | GLY149 |
| A | GLY27 |
| B | ILE150 |
| A | ALA28 |
| A | ASP30 |
| A | ILE32 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | HOH1001 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 502 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD A 504 |
| Chain | Residue |
| A | THR12 |
| A | LYS14 |
| A | GLY68 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 508 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 510 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 514 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 515 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 516 |
| Chain | Residue |
| A | IOD515 |
| A | HOH1029 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD A 518 |
| Chain | Residue |
| A | GLN18 |
| A | SER37 |
| B | IOD517 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 532 |
| Chain | Residue |
| A | PRO39 |
| A | GLY40 |
| A | ARG41 |
| A | TYR59 |
| A | ASP60 |
| A | GLU61 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD B 501 |
| Chain | Residue |
| B | TRP106 |
| B | LYS155 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD B 503 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD B 505 |
| Chain | Residue |
| B | ILE163 |
| B | HOH1111 |
| site_id | BC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD B 506 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD B 507 |
| Chain | Residue |
| B | THR112 |
| B | IOD506 |
| site_id | BC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD B 511 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD B 512 |
| Chain | Residue |
| B | THR174 |
| B | ASN188 |
| B | HOH1062 |
| site_id | BC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD B 513 |
| site_id | CC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD B 517 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 531 |
| Chain | Residue |
| A | GLN2 |
| A | THR4 |
| A | TRP6 |
| A | GLY51 |
| B | ILE154 |
| B | PRO179 |
| B | HOH1091 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTII |
| Chain | Residue | Details |
| B | ALA122-ILE133 | |
| A | ALA22-ILE33 | |
