3S1V

Transaldolase from Thermoplasma acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004801	molecular_function	transaldolase activity
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0006098	biological_process	pentose-phosphate shunt
A	0016740	molecular_function	transferase activity
A	0016832	molecular_function	aldehyde-lyase activity
B	0004801	molecular_function	transaldolase activity
B	0005737	cellular_component	cytoplasm
B	0005975	biological_process	carbohydrate metabolic process
B	0006098	biological_process	pentose-phosphate shunt
B	0016740	molecular_function	transferase activity
B	0016832	molecular_function	aldehyde-lyase activity
C	0004801	molecular_function	transaldolase activity
C	0005737	cellular_component	cytoplasm
C	0005975	biological_process	carbohydrate metabolic process
C	0006098	biological_process	pentose-phosphate shunt
C	0016740	molecular_function	transferase activity
C	0016832	molecular_function	aldehyde-lyase activity
D	0004801	molecular_function	transaldolase activity
D	0005737	cellular_component	cytoplasm
D	0005975	biological_process	carbohydrate metabolic process
D	0006098	biological_process	pentose-phosphate shunt
D	0016740	molecular_function	transferase activity
D	0016832	molecular_function	aldehyde-lyase activity
E	0004801	molecular_function	transaldolase activity
E	0005737	cellular_component	cytoplasm
E	0005975	biological_process	carbohydrate metabolic process
E	0006098	biological_process	pentose-phosphate shunt
E	0016740	molecular_function	transferase activity
E	0016832	molecular_function	aldehyde-lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL A 224

Chain	Residue
A	ASP137
E	ARG176
E	HOH246
A	ASN170
A	ILE172
A	HIS173
A	ARG176
A	HOH240
E	ASN170
E	ILE172
E	HIS173

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL B 224

Chain	Residue
B	ASP137
B	ASN170
B	ILE172
B	HIS173
B	ARG176
D	ASN170
D	ILE172
D	HIS173
D	ARG176
D	HOH253

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 225

Chain	Residue
A	ARG176
A	VAL179
A	ILE180
A	HOH692

---

site_id	AC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE F6R C 224

Chain	Residue
C	ASP6
C	THR26
C	THR27
C	ASN28
C	LYS86
C	ASN108
C	THR110
C	SER130
C	PHE132
C	ARG135
C	ALA166
C	SER167
C	HOH270
C	HOH483
C	HOH579
C	HOH597

---

site_id	AC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE F6R A 226

Chain	Residue
A	ASP6
A	THR26
A	THR27
A	ASN28
A	LYS86
A	ASN108
A	THR110
A	SER130
A	PHE132
A	ARG135
A	ALA166
A	SER167
A	ARG169
A	HOH245
A	HOH247

---

site_id	AC6
Number of Residues	15
Details	BINDING SITE FOR RESIDUE F6R B 225

Chain	Residue
B	ASP6
B	THR26
B	THR27
B	ASN28
B	LYS86
B	THR110
B	SER130
B	PHE132
B	ARG135
B	ALA166
B	SER167
B	ARG169
B	HOH253
B	HOH267
B	HOH683

---

site_id	AC7
Number of Residues	15
Details	BINDING SITE FOR RESIDUE F6R D 224

Chain	Residue
D	ASP6
D	THR27
D	ASN28
D	LYS86
D	ASN108
D	THR110
D	SER130
D	PHE132
D	ARG135
D	ALA166
D	SER167
D	ARG169
D	HOH258
D	HOH264
D	HOH277

---

site_id	AC8
Number of Residues	14
Details	BINDING SITE FOR RESIDUE F6R E 224

Chain	Residue
E	HOH760
E	ASP6
E	THR27
E	ASN28
E	LYS86
E	THR110
E	SER130
E	PHE132
E	ARG135
E	ALA166
E	SER167
E	ARG169
E	HOH345
E	HOH599

---

Functional Information from PROSITE/UniProt

site_id	PS00958
Number of Residues	18
Details	TRANSALDOLASE_2 Transaldolase active site. AvVKIPmTeDGLrAiKtL

Chain	Residue	Details
A	ALA83-LEU100

---

site_id	PS01054
Number of Residues	9
Details	TRANSALDOLASE_1 Transaldolase signature 1. GVTTNPTLI

Chain	Residue	Details
A	GLY24-ILE32

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	ACT_SITE: Schiff-base intermediate with substrate => ECO:0000250

Chain	Residue	Details
A	LYS86
B	LYS86
C	LYS86
D	LYS86
E	LYS86

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