3S0X
The crystal structure of GxGD membrane protease FlaK
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016020 | cellular_component | membrane |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 72 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | MSE501 | |
| A | LEU547-ASP549 | |
| A | VAL590-VAL610 | |
| A | PRO717-PHE730 | |
| B | MSE501 | |
| B | LEU547-ASP549 | |
| B | VAL590-VAL610 | |
| B | PRO717-PHE730 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 218 |
| Details | TRANSMEM: Helical => ECO:0000305 |
| Chain | Residue | Details |
| A | ILE502-ASP518 | |
| B | ASP579-LEU589 | |
| B | PRO611-ASN639 | |
| B | LEU705-THR716 | |
| A | ILE524-THR546 | |
| A | TYR550-LEU572 | |
| A | ASP579-LEU589 | |
| A | PRO611-ASN639 | |
| A | LEU705-THR716 | |
| B | ILE502-ASP518 | |
| B | ILE524-THR546 | |
| B | TYR550-LEU572 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 146 |
| Details | TOPO_DOM: Extracellular => ECO:0000305 |
| Chain | Residue | Details |
| A | PHE519-GLU523 | |
| A | SER573-GLY578 | |
| A | GLY640-PRO704 | |
| B | PHE519-GLU523 | |
| B | SER573-GLY578 | |
| B | GLY640-PRO704 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | SITE: Essential for catalysis => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP518 | |
| A | ASP579 | |
| B | ASP518 | |
| B | ASP579 |
