3S0K
Crystal Structure of Human Glycolipid Transfer Protein complexed with glucosylceramide containing oleoyl acyl chain (18:1)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006869 | biological_process | lipid transport |
| A | 0008289 | molecular_function | lipid binding |
| A | 0017089 | molecular_function | glycolipid transfer activity |
| A | 0035627 | biological_process | ceramide transport |
| A | 0035902 | biological_process | response to immobilization stress |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046317 | biological_process | regulation of glucosylceramide biosynthetic process |
| A | 0046836 | biological_process | glycolipid transport |
| A | 0051861 | molecular_function | glycolipid binding |
| A | 0106254 | molecular_function | lipid sensor activity |
| A | 0120009 | biological_process | intermembrane lipid transfer |
| A | 0120013 | molecular_function | lipid transfer activity |
| A | 1902387 | molecular_function | ceramide 1-phosphate binding |
| A | 1902388 | molecular_function | ceramide 1-phosphate transfer activity |
| A | 1902389 | biological_process | ceramide 1-phosphate transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE 03F A 210 |
| Chain | Residue |
| A | LEU30 |
| A | TRP96 |
| A | GLY100 |
| A | PHE107 |
| A | LEU108 |
| A | LEU136 |
| A | HIS140 |
| A | ALA151 |
| A | TYR207 |
| A | VAL209 |
| A | HOH215 |
| A | PHE33 |
| A | HOH273 |
| A | HOH379 |
| A | HOH397 |
| A | HOH422 |
| A | HOH468 |
| A | PHE34 |
| A | LEU37 |
| A | PHE42 |
| A | ILE45 |
| A | ASP48 |
| A | ASN52 |
| A | LEU92 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI A 240 |
| Chain | Residue |
| A | HIS7 |
| A | GLU25 |
| A | HIS29 |
| A | HIS120 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Repeat: {"description":"1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Repeat: {"description":"2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 21 |
| Details | Region: {"description":"2 X 12 AA approximate tandem repeats"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15329726","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1SX6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
