3RSW

Crystal Structure of Heart Fatty Acid Binding Protein (FABP3)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005319	molecular_function	lipid transporter activity
A	0005324	molecular_function	long-chain fatty acid transmembrane transporter activity
A	0005504	molecular_function	fatty acid binding
A	0005515	molecular_function	protein binding
A	0005615	cellular_component	extracellular space
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006631	biological_process	fatty acid metabolic process
A	0008092	molecular_function	cytoskeletal protein binding
A	0008285	biological_process	negative regulation of cell population proliferation
A	0008289	molecular_function	lipid binding
A	0009410	biological_process	response to xenobiotic stimulus
A	0015909	biological_process	long-chain fatty acid transport
A	0016528	cellular_component	sarcoplasm
A	0019433	biological_process	triglyceride catabolic process
A	0032365	biological_process	intracellular lipid transport
A	0032868	biological_process	response to insulin
A	0036041	molecular_function	long-chain fatty acid binding
A	0042632	biological_process	cholesterol homeostasis
A	0046320	biological_process	regulation of fatty acid oxidation
A	0050543	molecular_function	icosatetraenoic acid binding
A	0055091	biological_process	phospholipid homeostasis
A	0070062	cellular_component	extracellular exosome
A	0070538	molecular_function	oleic acid binding
A	0070542	biological_process	response to fatty acid
A	0071073	biological_process	positive regulation of phospholipid biosynthetic process
A	0140214	biological_process	positive regulation of long-chain fatty acid import into cell
B	0005319	molecular_function	lipid transporter activity
B	0005324	molecular_function	long-chain fatty acid transmembrane transporter activity
B	0005504	molecular_function	fatty acid binding
B	0005515	molecular_function	protein binding
B	0005615	cellular_component	extracellular space
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006631	biological_process	fatty acid metabolic process
B	0008092	molecular_function	cytoskeletal protein binding
B	0008285	biological_process	negative regulation of cell population proliferation
B	0008289	molecular_function	lipid binding
B	0009410	biological_process	response to xenobiotic stimulus
B	0015909	biological_process	long-chain fatty acid transport
B	0016528	cellular_component	sarcoplasm
B	0019433	biological_process	triglyceride catabolic process
B	0032365	biological_process	intracellular lipid transport
B	0032868	biological_process	response to insulin
B	0036041	molecular_function	long-chain fatty acid binding
B	0042632	biological_process	cholesterol homeostasis
B	0046320	biological_process	regulation of fatty acid oxidation
B	0050543	molecular_function	icosatetraenoic acid binding
B	0055091	biological_process	phospholipid homeostasis
B	0070062	cellular_component	extracellular exosome
B	0070538	molecular_function	oleic acid binding
B	0070542	biological_process	response to fatty acid
B	0071073	biological_process	positive regulation of phospholipid biosynthetic process
B	0140214	biological_process	positive regulation of long-chain fatty acid import into cell

Functional Information from PROSITE/UniProt

site_id	PS00214
Number of Residues	18
Details	FABP Cytosolic fatty-acid binding proteins signature. GTWkLvdSkNFDdYMKSL

Chain	Residue	Details
A	GLY7-LEU24

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"7922029","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1HMT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N-acetylvaline","evidences":[{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P07483","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine; by Tyr-kinases","evidences":[{"source":"UniProtKB","id":"P07483","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P07483","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---