3REO

Monolignol O-methyltransferase (MOMT)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008168	molecular_function	methyltransferase activity
A	0008171	molecular_function	O-methyltransferase activity
A	0032259	biological_process	methylation
A	0046983	molecular_function	protein dimerization activity
A	0050630	molecular_function	(iso)eugenol O-methyltransferase activity
A	0102719	molecular_function	S-adenosyl-L-methionine:eugenol-O-methyltransferase activity
B	0008168	molecular_function	methyltransferase activity
B	0008171	molecular_function	O-methyltransferase activity
B	0032259	biological_process	methylation
B	0046983	molecular_function	protein dimerization activity
B	0050630	molecular_function	(iso)eugenol O-methyltransferase activity
B	0102719	molecular_function	S-adenosyl-L-methionine:eugenol-O-methyltransferase activity
C	0008168	molecular_function	methyltransferase activity
C	0008171	molecular_function	O-methyltransferase activity
C	0032259	biological_process	methylation
C	0046983	molecular_function	protein dimerization activity
C	0050630	molecular_function	(iso)eugenol O-methyltransferase activity
C	0102719	molecular_function	S-adenosyl-L-methionine:eugenol-O-methyltransferase activity
D	0008168	molecular_function	methyltransferase activity
D	0008171	molecular_function	O-methyltransferase activity
D	0032259	biological_process	methylation
D	0046983	molecular_function	protein dimerization activity
D	0050630	molecular_function	(iso)eugenol O-methyltransferase activity
D	0102719	molecular_function	S-adenosyl-L-methionine:eugenol-O-methyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE SAH A 370

Chain	Residue
A	PHE166
A	PHE256
A	LYS268
A	ILE270
A	ASP273
A	TRP274
A	HOH376
A	HOH377
A	HOH389
A	HOH409
A	MET183
A	SER187
A	GLY211
A	ASP234
A	LEU235
A	VAL238
A	ASP254
A	MET255

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE EUG B 369

Chain	Residue
B	LEU133
B	ALA134
B	LEU139
B	ILE165
B	PHE166
B	MET183
B	HIS272
B	ASP273
B	LEU322
B	TYR326
B	ASN327

---

site_id	AC3
Number of Residues	21
Details	BINDING SITE FOR RESIDUE SAH B 370

Chain	Residue
B	PHE166
B	PHE179
B	MET183
B	SER187
B	GLY211
B	GLY213
B	ASP234
B	LEU235
B	VAL238
B	ASP254
B	MET255
B	PHE256
B	LYS268
B	ILE270
B	ASP273
B	TRP274
B	HOH374
B	HOH382
B	HOH398
B	HOH417
B	HOH418

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EUG C 369

Chain	Residue
C	ALA134
C	LEU139
C	TRP269
C	HIS272
C	ASP273
C	TYR326
C	ASN327
C	SAH370

---

site_id	AC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE SAH C 370

Chain	Residue
C	MET183
C	SER187
C	GLY211
C	ASP234
C	VAL238
C	ASP254
C	MET255
C	LYS268
C	ILE270
C	ASP273
C	EUG369
C	HOH378
C	HOH397
C	HOH399
C	HOH400
C	HOH405
C	HOH407

---

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EUG D 369

Chain	Residue
D	LEU133
D	LEU139
D	ILE165
D	PHE166
D	PHE179
D	TRP269
D	HIS272
D	TYR326
D	ASN327
D	HOH399

---

site_id	AC7
Number of Residues	16
Details	BINDING SITE FOR RESIDUE SAH D 370

Chain	Residue
D	HOH378
D	HOH382
D	PHE166
D	SER187
D	GLY211
D	GLY213
D	ASP234
D	LEU235
D	VAL238
D	ASP254
D	MET255
D	PHE256
D	LYS268
D	ILE270
D	ASP273
D	TRP274

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU01020

Chain	Residue	Details
A	HIS272
B	HIS272
C	HIS272
D	HIS272

---

site_id	SWS_FT_FI2
Number of Residues	20
Details	BINDING: BINDING => ECO:0000269|PubMed:22851762

Chain	Residue	Details
A	SER187
B	LYS268
C	SER187
C	GLY211
C	ASP234
C	ASP254
C	LYS268
D	SER187
D	GLY211
D	ASP234
D	ASP254
A	GLY211
D	LYS268
A	ASP234
A	ASP254
A	LYS268
B	SER187
B	GLY211
B	ASP234
B	ASP254

---