3RBQ

Co-crystal structure of human UNC119 (retina gene 4) and an N-terminal Transducin-alpha mimicking peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007399	biological_process	nervous system development
B	0007399	biological_process	nervous system development
C	0007399	biological_process	nervous system development
D	0007399	biological_process	nervous system development
E	0007399	biological_process	nervous system development
F	0007399	biological_process	nervous system development

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE DAO G 500

Chain	Residue
A	PHE91
G	ALA502
G	GLY503
A	TYR131
A	GLU163
A	HIS165
A	PHE175
A	TYR194
A	PHE196
A	TYR234
G	GLY501

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE DAO H 500

Chain	Residue
B	VAL129
B	TYR131
B	GLU163
B	HIS165
B	PHE175
B	TYR194
B	PHE196
B	TYR234
H	GLY501
H	ALA502
H	GLY503

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE DAO I 500

Chain	Residue
C	TYR131
C	GLU163
C	PHE196
C	TYR234
I	GLY501
I	ALA502
I	GLY503

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE DAO J 500

Chain	Residue
D	TYR131
D	GLU163
D	TYR194
D	TYR234
J	GLY501
J	ALA502
J	GLY503

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE DAO K 500

Chain	Residue
E	TYR131
E	GLU163
E	TYR194
E	PHE196
E	TYR234
K	GLY501
K	ALA502
K	GLY503

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE DAO L 500

Chain	Residue
F	PHE91
F	TYR131
F	GLU163
F	PRO197
F	TYR234
L	GLY501
L	ALA502
L	GLY503

---

site_id	AC7
Number of Residues	17
Details	BINDING SITE FOR CHAIN G OF GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1

Chain	Residue
A	ASP87
A	PHE88
A	PHE91
A	ILE105
A	LYS106
A	LYS107
A	GLY126
A	ARG127
A	TYR131
A	GLU163
A	SER218
A	TYR220
A	ASN230
A	HOH294
A	HOH784
G	DAO500
G	HOH776

---

site_id	AC8
Number of Residues	16
Details	BINDING SITE FOR CHAIN H OF GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1

Chain	Residue
B	PHE88
B	PHE91
B	ILE105
B	LYS107
B	GLY126
B	ARG127
B	PHE128
B	VAL129
B	TYR131
B	GLU163
B	SER218
B	TYR220
B	ASN230
B	HOH318
H	HOH281
H	DAO500

---

site_id	AC9
Number of Residues	10
Details	BINDING SITE FOR CHAIN I OF GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1

Chain	Residue
C	PHE91
C	ARG127
C	PHE128
C	TYR131
C	GLU163
C	SER218
C	TYR220
C	ASN230
C	HOH276
I	DAO500

---

site_id	BC1
Number of Residues	12
Details	BINDING SITE FOR CHAIN J OF GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1

Chain	Residue
D	PHE128
D	TYR131
D	GLU163
D	SER218
D	TYR220
D	ASN230
D	HOH252
J	DAO500
D	PHE88
D	PHE91
D	GLY126
D	ARG127

---

site_id	BC2
Number of Residues	9
Details	BINDING SITE FOR CHAIN K OF GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1

Chain	Residue
E	PHE91
E	VAL129
E	TYR131
E	GLU163
E	SER218
E	TYR220
E	ASN230
E	HOH660
K	DAO500

---

site_id	BC3
Number of Residues	23
Details	BINDING SITE FOR CHAIN L OF GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1

Chain	Residue
B	SER200
B	HOH265
F	PHE88
F	PHE91
F	ILE105
F	LYS106
F	LYS107
F	PRO108
F	PRO123
F	ALA125
F	GLY126
F	ARG127
F	PHE128
F	VAL129
F	TYR131
F	GLU163
F	SER218
F	TYR220
F	MET228
F	ASN230
L	HOH25
L	HOH97
L	DAO500

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Lipidation: {"description":"N-myristoyl glycine","evidences":[{"source":"PubMed","id":"21642972","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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