3RB6

Dpo4 extension ternary complex with 3'-terminal primer A base opposite the 3-methylcytosine (m3c) lesion

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034061	molecular_function	DNA polymerase activity
A	0042276	biological_process	error-prone translesion synthesis
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0003677	molecular_function	DNA binding
B	0003684	molecular_function	damaged DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005737	cellular_component	cytoplasm
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006281	biological_process	DNA repair
B	0006974	biological_process	DNA damage response
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0034061	molecular_function	DNA polymerase activity
B	0042276	biological_process	error-prone translesion synthesis
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE DGT A 414

Chain	Residue
A	ASP7
A	ASP105
A	LYS159
A	HOH362
A	CA415
A	CA416
D	2DA814
E	DC905
E	ME6906
A	PHE8
A	TYR10
A	PHE11
A	TYR12
A	ALA44
A	THR45
A	TYR48
A	ARG51

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EPE A 342

Chain	Residue
A	SER103
A	ILE104
A	ARG240
A	HOH355
D	DA812
D	DG813
D	2DA814
E	DC907
E	DT908
E	DA909

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 415

Chain	Residue
A	ASP7
A	ASP105
A	GLU106
A	DGT414
A	CA416
D	HOH65
D	2DA814

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 416

Chain	Residue
A	ASP7
A	PHE8
A	ASP105
A	DGT414
A	CA415

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 417

Chain	Residue
A	ALA181
A	ILE186
A	HOH343
A	HOH358
D	HOH5
D	HOH40

---

site_id	AC6
Number of Residues	18
Details	BINDING SITE FOR RESIDUE DGT B 1414

Chain	Residue
B	ASP1007
B	PHE1008
B	TYR1010
B	PHE1011
B	TYR1012
B	VAL1032
B	ALA1044
B	THR1045
B	TYR1048
B	ARG1051
B	ASP1105
B	LYS1159
B	CA1415
B	CA1416
H	HOH31
H	2DA1814
J	DC1905
J	ME61906

---

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA B 1415

Chain	Residue
B	HOH6
B	ASP1007
B	ASP1105
B	GLU1106
B	DGT1414
B	CA1416
H	2DA1814

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA B 1416

Chain	Residue
B	ASP1007
B	PHE1008
B	ASP1105
B	DGT1414
B	CA1415

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA B 1417

Chain	Residue
B	HOH8
B	HOH9
B	ALA1181
B	ILE1186
H	HOH3

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	368
Details	Domain: {"description":"UmuC"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Site: {"description":"Substrate discrimination"}

Chain

Residue

Details

---