Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004019 | molecular_function | adenylosuccinate synthase activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0044208 | biological_process | 'de novo' AMP biosynthetic process |
| A | 0046040 | biological_process | IMP metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CIT A 421 |
| Chain | Residue |
| A | VAL269 |
| A | HOH595 |
| A | GLY294 |
| A | VAL295 |
| A | SER296 |
| A | THR297 |
| A | ARG301 |
| A | HOH491 |
| A | HOH542 |
| A | HOH568 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGE A 422 |
| Chain | Residue |
| A | LYS285 |
| A | ASP332 |
| A | GLY333 |
| A | PHE334 |
| A | HOH545 |
| A | HOH651 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PGE A 423 |
| Chain | Residue |
| A | ASP98 |
| A | LEU149 |
| A | ILE197 |
| A | TYR345 |
| A | LYS346 |
| A | ASP356 |
| A | HOH486 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 424 |
| Chain | Residue |
| A | HIS143 |
| A | GLU147 |
| A | HOH621 |
| A | HOH628 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 425 |
| Chain | Residue |
| A | TYR95 |
| A | THR198 |
| A | HOH627 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 426 |
| Chain | Residue |
| A | LEU149 |
| A | LYS187 |
| A | ASN190 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 427 |
Functional Information from PROSITE/UniProt
| site_id | PS00513 |
| Number of Residues | 12 |
| Details | ADENYLOSUCCIN_SYN_2 Adenylosuccinate synthetase active site. GIGPsYadKinR |
| Chain | Residue | Details |
| A | GLY129-ARG140 | |
| site_id | PS01266 |
| Number of Residues | 8 |
| Details | ADENYLOSUCCIN_SYN_1 Adenylosuccinate synthetase GTP-binding site. QWGDEGKG |
| Chain | Residue | Details |
| A | GLN11-GLY18 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00011","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00011","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00011","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"HAMAP-Rule","id":"MF_00011","evidenceCode":"ECO:0000255"}]} |
3R7T
