3R5A

Pseudomonas aeruginosa DapD (PA3666) in complex with D-2-aminopimelate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005737	cellular_component	cytoplasm
A	0008652	biological_process	amino acid biosynthetic process
A	0008666	molecular_function	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity
A	0009085	biological_process	lysine biosynthetic process
A	0009089	biological_process	lysine biosynthetic process via diaminopimelate
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0019877	biological_process	diaminopimelate biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0005737	cellular_component	cytoplasm
B	0008652	biological_process	amino acid biosynthetic process
B	0008666	molecular_function	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity
B	0009085	biological_process	lysine biosynthetic process
B	0009089	biological_process	lysine biosynthetic process via diaminopimelate
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0019877	biological_process	diaminopimelate biosynthetic process
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0005737	cellular_component	cytoplasm
C	0008652	biological_process	amino acid biosynthetic process
C	0008666	molecular_function	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity
C	0009085	biological_process	lysine biosynthetic process
C	0009089	biological_process	lysine biosynthetic process via diaminopimelate
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0019877	biological_process	diaminopimelate biosynthetic process
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0005737	cellular_component	cytoplasm
D	0008652	biological_process	amino acid biosynthetic process
D	0008666	molecular_function	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity
D	0009085	biological_process	lysine biosynthetic process
D	0009089	biological_process	lysine biosynthetic process via diaminopimelate
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
D	0019877	biological_process	diaminopimelate biosynthetic process
D	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0005737	cellular_component	cytoplasm
E	0008652	biological_process	amino acid biosynthetic process
E	0008666	molecular_function	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity
E	0009085	biological_process	lysine biosynthetic process
E	0009089	biological_process	lysine biosynthetic process via diaminopimelate
E	0016740	molecular_function	transferase activity
E	0016746	molecular_function	acyltransferase activity
E	0019877	biological_process	diaminopimelate biosynthetic process
E	0046872	molecular_function	metal ion binding
F	0000287	molecular_function	magnesium ion binding
F	0005737	cellular_component	cytoplasm
F	0008652	biological_process	amino acid biosynthetic process
F	0008666	molecular_function	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity
F	0009085	biological_process	lysine biosynthetic process
F	0009089	biological_process	lysine biosynthetic process via diaminopimelate
F	0016740	molecular_function	transferase activity
F	0016746	molecular_function	acyltransferase activity
F	0019877	biological_process	diaminopimelate biosynthetic process
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE P0A A 351

Chain	Residue
A	PHE129
C	GLU221
A	ARG191
A	ASN209
A	SER225
A	ALA226
A	HOH381
A	HOH878
C	ARG183
C	MET203

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE P0A A 345

Chain	Residue
A	ARG183
A	MET203
A	MET219
A	GLU221
A	HOH952
B	PHE129
B	ARG191
B	PHE207
B	ASN209
B	SER225
B	ALA226

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE P0A C 351

Chain	Residue
B	ARG183
B	MET203
B	GLU221
C	PHE129
C	ARG191
C	ASN209
C	SER225
C	ALA226
C	HOH800
C	HOH895

---

site_id	AC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL A 346

Chain	Residue
A	ASN139
A	GLU163
A	HOH359
A	HOH375
A	HOH428
A	HOH818
B	ASN139
B	GLU163
B	HOH998
C	ASN139
C	GLU163

---

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE P0A D 351

Chain	Residue
D	ARG191
D	ASN209
D	SER225
D	ALA226
D	GLY244
D	THR245
D	LEU246
F	ARG183
F	MET203
F	MET219
F	GLU221

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE P0A E 351

Chain	Residue
D	ARG183
D	GLU221
E	PHE129
E	ARG191
E	ASN209
E	SER225
E	ALA226

---

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL E 345

Chain	Residue
D	ASN139
D	HOH382
E	ASN139
E	GLU163
E	HOH376
F	ASN139
F	GLU163

---

site_id	AC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE P0A F 351

Chain	Residue
E	ARG183
E	MET219
E	GLU221
F	PHE129
F	ARG191
F	PHE207
F	ASN209
F	SER225
F	ALA226

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Acyl-anhydride intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_02122","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02122","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	63
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22359568","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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