3R3L

Structure of NP protein from Lassa AV strain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0016787	molecular_function	hydrolase activity
A	0019013	cellular_component	viral nucleocapsid
A	0019029	cellular_component	helical viral capsid
A	0019049	biological_process	virus-mediated perturbation of host defense response
A	0030430	cellular_component	host cell cytoplasm
A	0039689	biological_process	negative stranded viral RNA replication
A	0039696	biological_process	RNA-templated viral transcription
A	0039724	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity
A	0046872	molecular_function	metal ion binding
A	1990904	cellular_component	ribonucleoprotein complex
B	0003723	molecular_function	RNA binding
B	0016787	molecular_function	hydrolase activity
B	0019013	cellular_component	viral nucleocapsid
B	0019029	cellular_component	helical viral capsid
B	0019049	biological_process	virus-mediated perturbation of host defense response
B	0030430	cellular_component	host cell cytoplasm
B	0039689	biological_process	negative stranded viral RNA replication
B	0039696	biological_process	RNA-templated viral transcription
B	0039724	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity
B	0046872	molecular_function	metal ion binding
B	1990904	cellular_component	ribonucleoprotein complex
C	0003723	molecular_function	RNA binding
C	0016787	molecular_function	hydrolase activity
C	0019013	cellular_component	viral nucleocapsid
C	0019029	cellular_component	helical viral capsid
C	0019049	biological_process	virus-mediated perturbation of host defense response
C	0030430	cellular_component	host cell cytoplasm
C	0039689	biological_process	negative stranded viral RNA replication
C	0039696	biological_process	RNA-templated viral transcription
C	0039724	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity
C	0046872	molecular_function	metal ion binding
C	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 583

Chain	Residue
A	ASP204
A	HIS226
B	ASP204
B	SER225
B	HIS226

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MN A 584

Chain	Residue
A	ASP389
A	GLU391
A	ASP533

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 585

Chain	Residue
A	CYS506
A	HIS509
A	CYS529
A	GLU399

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN B 583

Chain	Residue
B	ASP389
B	ILE390
B	GLU391
B	ASP533

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MN B 584

Chain	Residue
B	ARG68
B	ASN173
B	GLN175

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site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 585

Chain	Residue
B	GLU399
B	CYS506
B	HIS509
B	CYS529

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site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN C 583

Chain	Residue
C	ASP389
C	ILE390
C	GLU391
C	ASP533

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site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 584

Chain	Residue
C	GLU399
C	CYS506
C	HIS509
C	CYS529

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