3QZV

Crystal Structure of BPTF PHD-linker-bromo in complex with histone H4K12ac peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0016589	cellular_component	NURF complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 175

Chain	Residue
A	CYS11
A	CYS13
A	HIS34
A	CYS37

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 176

Chain	Residue
A	CYS26
A	CYS29
A	CYS53
A	CYS56

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Functional Information from PROSITE/UniProt

site_id	PS00633
Number of Residues	58
Details	BROMODOMAIN_1 Bromodomain signature. AwpFlepvDpndap..DYYgvIkepMdlatMeervqrry..Yekltefvadmtk.IfdNCryY

Chain	Residue	Details
A	ALA90-TYR147

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site_id	PS01186
Number of Residues	16
Details	EGF_2 EGF-like domain signature 2. CiCktPYdeskfyigC

Chain	Residue	Details
A	CYS11-CYS26

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site_id	PS01359
Number of Residues	46
Details	ZF_PHD_1 Zinc finger PHD-type signature. Ci.Cktpydeskfy...................................IgCdr..Cqnw.YHgrCvgilqseaelide................................YvCpqC

Chain	Residue	Details
A	CYS11-CYS56

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: N6-propionyllysine; alternate => ECO:0000269|PubMed:17267393

Chain	Residue	Details
C	LYS8
C	LYS16

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435

Chain	Residue	Details
C	ALY12
A	TYR17
A	TYR23
A	TRP32

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site_id	SWS_FT_FI3
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25218447

Chain	Residue	Details
C	ALY12

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