Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004743 | molecular_function | pyruvate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006096 | biological_process | glycolytic process |
| A | 0006950 | biological_process | response to stress |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030955 | molecular_function | potassium ion binding |
| A | 0046872 | molecular_function | metal ion binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004743 | molecular_function | pyruvate kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006096 | biological_process | glycolytic process |
| D | 0006950 | biological_process | response to stress |
| D | 0016301 | molecular_function | kinase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0030955 | molecular_function | potassium ion binding |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE S62 D 499 |
| Chain | Residue |
| D | THR26 |
| D | PRO29 |
| D | ARG49 |
| D | ASN51 |
| D | HIS54 |
| D | SER330 |
| D | GLY331 |
| D | ALA334 |
| D | HOH544 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 D 500 |
| Chain | Residue |
| D | SER1 |
| D | TYR360 |
| D | VAL361 |
| D | ASN364 |
| D | HOH553 |
| D | HOH599 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 D 501 |
| Chain | Residue |
| D | SER400 |
| D | ASN401 |
| D | THR402 |
| D | ARG404 |
| D | SER405 |
| D | ASP482 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE S62 A 499 |
| Chain | Residue |
| A | THR26 |
| A | PRO29 |
| A | ARG49 |
| A | ASN51 |
| A | SER330 |
| A | GLY331 |
| A | HOH564 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 500 |
| Chain | Residue |
| A | SER1 |
| A | TYR360 |
| A | VAL361 |
| A | ASN364 |
| A | HOH557 |
| A | HOH566 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 501 |
| Chain | Residue |
| A | SER400 |
| A | ASN401 |
| A | THR402 |
| A | ARG404 |
| A | SER405 |
Functional Information from PROSITE/UniProt
| site_id | PS00110 |
| Number of Residues | 13 |
| Details | PYRUVATE_KINASE Pyruvate kinase active site signature. ImIICKIENhQGV |
| Chain | Residue | Details |
| D | ILE233-VAL245 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P14618","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer"} |
