3QTC

Crystal structure of the catalytic domain of MmOmeRS, an O-methyl tyrosyl-tRNA synthetase evolved from Methanosarcina mazei PylRS, complexed with O-methyl tyrosine and AMP-PNP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0043039	biological_process	tRNA aminoacylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 800

Chain	Residue
A	HOH487
A	HOH490
A	HOH492
A	HOH494
A	ANP810

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 801

Chain	Residue
A	ANP810
A	GLU396
A	SER399
A	HOH498
A	HOH521

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE 0A1 A 811

Chain	Residue
A	HOH70
A	MET300
A	THR302
A	TRP348
A	SER399
A	LEU401
A	GLY419
A	ALA420
A	HOH545
A	EDO812

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 812

Chain	Residue
A	THR302
A	TYR306
A	LEU401
A	TRP417
A	HOH512
A	0A1811

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 813

Chain	Residue
A	LYS429
A	ASP433
A	PHE434

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 814

Chain	Residue
A	TYR242
A	LEU246
A	GLU249
A	LYS431
A	HIS432

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 815

Chain	Residue
A	HOH23
A	ASN241
A	ARG439
A	ALA440
A	ASN448
A	GLY449

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 817

Chain	Residue
A	TYR272
A	ASN307
A	ARG310
A	LYS311
A	GLU357
A	GLU444

---

site_id	AC9
Number of Residues	25
Details	BINDING SITE FOR RESIDUE ANP A 810

Chain	Residue
A	HOH1
A	HOH6
A	HOH79
A	HOH130
A	HOH138
A	ARG330
A	GLU332
A	HIS338
A	LEU339
A	PHE342
A	MET344
A	GLU396
A	LEU397
A	SER398
A	SER399
A	GLY421
A	GLY423
A	ARG426
A	HOH487
A	HOH490
A	HOH492
A	HOH494
A	HOH498
A	MG800
A	MG801

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