Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1000 |
| Chain | Residue |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU80 |
| A | HOH2020 |
| A | HOH2034 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | SER195 |
| A | IMD1007 |
| A | BEN1010 |
| A | HIS57 |
| A | GLN192 |
| A | GLY193 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1002 |
| Chain | Residue |
| A | ARG66 |
| A | SER166 |
| A | SER167 |
| A | SER170 |
| A | EDO1005 |
| A | HOH2039 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1003 |
| Chain | Residue |
| A | LYS169 |
| A | PRO173 |
| A | GLY174 |
| A | GLN240 |
| A | HOH2025 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1004 |
| Chain | Residue |
| A | TYR20 |
| A | CYS22 |
| A | THR26 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 1005 |
| Chain | Residue |
| A | ASN34 |
| A | GLY38 |
| A | TYR39 |
| A | HIS40 |
| A | ILE73 |
| A | SER164 |
| A | SER166 |
| A | SER167 |
| A | SO41002 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 1006 |
| Chain | Residue |
| A | THR177 |
| A | SER178 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IMD A 1007 |
| Chain | Residue |
| A | PHE41 |
| A | HIS57 |
| A | SO41001 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1008 |
| Chain | Residue |
| A | LYS145 |
| A | SER146 |
| A | SER147 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1009 |
| Chain | Residue |
| A | ASP153 |
| A | VAL154 |
| A | LYS156 |
| A | HOH2074 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE BEN A 1010 |
| Chain | Residue |
| A | ASP189 |
| A | SER190 |
| A | SER195 |
| A | SER214 |
| A | GLY219 |
| A | GLY226 |
| A | SO41001 |
| A | HOH2005 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU70 | |
| A | ASN72 | |
| A | VAL75 | |
| A | GLU80 | |
| A | ASP189 | |
| A | GLN192 | |
| A | SER195 | |
