3QEJ

S74E-dCK mutant in complex with UDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004136	molecular_function	deoxyadenosine kinase activity
A	0004137	molecular_function	deoxycytidine kinase activity
A	0004138	molecular_function	deoxyguanosine kinase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0006220	biological_process	pyrimidine nucleotide metabolic process
A	0008144	molecular_function	obsolete drug binding
A	0009224	biological_process	CMP biosynthetic process
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0019136	molecular_function	deoxynucleoside kinase activity
A	0042803	molecular_function	protein homodimerization activity
A	0043771	molecular_function	cytidine kinase activity
A	0106383	biological_process	dAMP salvage
A	1901135	biological_process	carbohydrate derivative metabolic process
A	1901293	biological_process	nucleoside phosphate biosynthetic process
B	0000166	molecular_function	nucleotide binding
B	0004136	molecular_function	deoxyadenosine kinase activity
B	0004137	molecular_function	deoxycytidine kinase activity
B	0004138	molecular_function	deoxyguanosine kinase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0006139	biological_process	nucleobase-containing compound metabolic process
B	0006220	biological_process	pyrimidine nucleotide metabolic process
B	0008144	molecular_function	obsolete drug binding
B	0009224	biological_process	CMP biosynthetic process
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0019136	molecular_function	deoxynucleoside kinase activity
B	0042803	molecular_function	protein homodimerization activity
B	0043771	molecular_function	cytidine kinase activity
B	0106383	biological_process	dAMP salvage
B	1901135	biological_process	carbohydrate derivative metabolic process
B	1901293	biological_process	nucleoside phosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE UDP A 401

Chain	Residue
A	ALA31
A	PHE242
A	LYS243
A	HOH296
A	ALA32
A	GLY33
A	LYS34
A	SER35
A	THR36
A	ARG188
A	ARG192
A	ASP241

---

site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE UDP B 402

Chain	Residue
B	ASN29
B	ALA31
B	ALA32
B	GLY33
B	LYS34
B	SER35
B	THR36
B	ARG188
B	ARG192
B	ASP241
B	PHE242
B	LYS243
B	HOH281
B	HOH286
B	HOH295

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	40
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine; by CK1","evidences":[{"source":"PubMed","id":"20637175","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20637175","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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