3Q95
Crystal structure of human estrogen receptor alpha LBD in complex with GRIP peptide and estriol
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ESL B 700 |
| Chain | Residue |
| B | HOH18 |
| B | LEU346 |
| B | GLU353 |
| B | LEU387 |
| B | ARG394 |
| B | HIS524 |
| B | LEU525 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ESL A 700 |
| Chain | Residue |
| A | LEU346 |
| A | GLU353 |
| A | LEU387 |
| A | ARG394 |
| A | HIS524 |
| A | LEU525 |
| A | HOH24 |
| A | MET343 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 555 |
| Chain | Residue |
| A | HOH7 |
| A | HOH22 |
| A | ARG352 |
| B | ARG352 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 702 |
| Chain | Residue |
| A | THR496 |
| A | LEU497 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 703 |
| Chain | Residue |
| A | ARG412 |
| A | LYS416 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE |
| Chain | Residue | Details |
| B | GLU353 | |
| B | ARG394 | |
| B | HIS524 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106 |
| Chain | Residue | Details |
| B | SER537 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| Chain | Residue | Details |
| B | CYS447 |
