3Q5E

crystal structure of human Atlastin-1 (residues 1-447) bound to GDP, crystal form 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
E	0003924	molecular_function	GTPase activity
E	0005525	molecular_function	GTP binding
G	0003924	molecular_function	GTPase activity
G	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE GDP A 3850

Chain	Residue
A	ARG77
A	ASP218
A	PRO272
A	VAL276
A	ALA277
A	ASN279
A	PRO280
A	MG448
A	LYS78
A	GLY79
A	LYS80
A	SER81
A	PHE82
A	GLU117
A	GLN148
A	ARG217

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 448

Chain	Residue
A	SER81
A	ASP146
A	GLN148
A	GDP3850

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GDP C 3850

Chain	Residue
C	ARG77
C	LYS78
C	GLY79
C	LYS80
C	SER81
C	PHE82
C	ARG217
C	ASP218
C	PRO272
C	VAL276
C	ASN279
C	PRO280

---

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 448

Chain	Residue
C	SER81

---

site_id	AC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE GDP E 3850

Chain	Residue
E	PHE76
E	ARG77
E	LYS78
E	GLY79
E	LYS80
E	SER81
E	PHE82
E	GLN148
E	ARG217
E	ASP218
E	PRO272
E	VAL276
E	ALA277
E	ASN279
E	PRO280

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG E 448

Chain	Residue
E	SER81

---

site_id	AC7
Number of Residues	14
Details	BINDING SITE FOR RESIDUE GDP G 3850

Chain	Residue
G	ALA75
G	ARG77
G	LYS78
G	GLY79
G	LYS80
G	SER81
G	PHE82
G	GLN148
G	ARG217
G	ASP218
G	HIS271
G	PRO272
G	VAL276
G	ASN279

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG G 448

Chain	Residue
G	SER81
G	GLN124
G	ASP146
G	GLN148

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	BINDING:

Chain	Residue	Details
A	GLY74
E	ARG118
E	ARG217
E	VAL276
G	GLY74
G	ARG118
G	ARG217
G	VAL276
A	ARG118
A	ARG217
A	VAL276
C	GLY74
C	ARG118
C	ARG217
C	VAL276
E	GLY74

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q8BH66

Chain	Residue	Details
A	SER10
G	SER10
G	SER22
G	SER23
A	SER22
A	SER23
C	SER10
C	SER22
C	SER23
E	SER10
E	SER22
E	SER23

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q6DD88

Chain	Residue	Details
A	LYS395
C	LYS395
E	LYS395
G	LYS395

---