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3Q4W

The structure of archaeal inorganic pyrophosphatase in complex with substrate

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0004427molecular_functioninorganic diphosphate phosphatase activity
A0005737cellular_componentcytoplasm
A0006796biological_processphosphate-containing compound metabolic process
A0016787molecular_functionhydrolase activity
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CA A 224
ChainResidue
AASP98
AASP103
AHOH205
APOP227
AHOH302

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CA A 225
ChainResidue
APOP227
AHOH228
AASP66
AASP71
AASP103
AHOH189

site_idAC3
Number of Residues19
DetailsBINDING SITE FOR RESIDUE POP A 227
ChainResidue
ALYS30
AARG44
ATYR56
AASP66
AASP71
AASP98
AASP103
ATYR140
ALYS141
AHOH205
ACA224
ACA225
AHOH228
AHOH230
ABR279
AHOH281
ANA283
ACA284
AHOH345

site_idAC4
Number of Residues7
DetailsBINDING SITE FOR RESIDUE BR A 279
ChainResidue
AGLU22
ATYR56
AGLY57
AASP71
APOP227
ANA283
AHOH317

site_idAC5
Number of Residues6
DetailsBINDING SITE FOR RESIDUE NA A 283
ChainResidue
AASP71
APOP227
AHOH228
ABR279
AHOH292
AHOH317

site_idAC6
Number of Residues8
DetailsBINDING SITE FOR RESIDUE CA A 284
ChainResidue
AASP66
AASP68
APOP227
AHOH280
AHOH281
AHOH448
AHOH450
AHOH451

Functional Information from PROSITE/UniProt
site_idPS00387
Number of Residues7
DetailsPPASE Inorganic pyrophosphatase signature. DGDPFDI
ChainResidueDetails
AASP66-ILE72

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PDB entries from 2024-10-30

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