3Q19

Human Glutathione Transferase O2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004364	molecular_function	glutathione transferase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006749	biological_process	glutathione metabolic process
A	0006805	biological_process	xenobiotic metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016740	molecular_function	transferase activity
A	0019852	biological_process	L-ascorbic acid metabolic process
A	0042802	molecular_function	identical protein binding
A	0045174	molecular_function	glutathione dehydrogenase (ascorbate) activity
A	0050610	molecular_function	methylarsonate reductase activity
A	0055114	biological_process	obsolete oxidation-reduction process
A	0070062	cellular_component	extracellular exosome
A	0071243	biological_process	cellular response to arsenic-containing substance
A	0098869	biological_process	cellular oxidant detoxification
B	0004364	molecular_function	glutathione transferase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006749	biological_process	glutathione metabolic process
B	0006805	biological_process	xenobiotic metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016740	molecular_function	transferase activity
B	0019852	biological_process	L-ascorbic acid metabolic process
B	0042802	molecular_function	identical protein binding
B	0045174	molecular_function	glutathione dehydrogenase (ascorbate) activity
B	0050610	molecular_function	methylarsonate reductase activity
B	0055114	biological_process	obsolete oxidation-reduction process
B	0070062	cellular_component	extracellular exosome
B	0071243	biological_process	cellular response to arsenic-containing substance
B	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GSH A 240

Chain	Residue
A	CYS32
A	PRO33
A	TYR34
A	LYS59
A	HIS71
A	ILE72
A	PRO73
A	GLU85
A	SER86

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 241

Chain	Residue
A	SER205
A	HOH243
A	HOH252

---

site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GSH B 240

Chain	Residue
B	CYS32
B	TYR34
B	LYS59
B	HIS71
B	ILE72
B	PRO73
B	GLU85
B	SER86
B	HOH292

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 241

Chain	Residue
A	HOH246
A	HOH304
B	SER205
B	HOH343

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	158
Details	Domain: {"description":"GST N-terminal"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Nucleophile"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22522127","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	125
Details	Domain: {"description":"GST C-terminal"}

Chain

Residue

Details

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