3Q0R
Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with p38alpha NREb
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 342 |
| Details | Domain: {"description":"PUM-HD","evidences":[{"source":"PROSITE-ProRule","id":"PRU00318","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 35 |
| Details | Repeat: {"description":"Pumilio 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 35 |
| Details | Repeat: {"description":"Pumilio 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 37 |
| Details | Repeat: {"description":"Pumilio 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 35 |
| Details | Repeat: {"description":"Pumilio 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 35 |
| Details | Repeat: {"description":"Pumilio 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 35 |
| Details | Repeat: {"description":"Pumilio 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 35 |
| Details | Repeat: {"description":"Pumilio 7","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 39 |
| Details | Repeat: {"description":"Pumilio 8","evidences":[{"source":"PROSITE-ProRule","id":"PRU00317","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21397187","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 12 |
| Details | Region: {"description":"Adenine-nucleotide binding in RNA target","evidences":[{"source":"UniProtKB","id":"Q14671","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 12 |
| Details | Region: {"description":"Uracil-nucleotide binding in RNA target","evidences":[{"source":"UniProtKB","id":"Q14671","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 4 |
| Details | Region: {"description":"Non-specific-nucleotide binding in RNA target","evidences":[{"source":"UniProtKB","id":"Q14671","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 4 |
| Details | Region: {"description":"Guanine-nucleotide binding in RNA target","evidences":[{"source":"UniProtKB","id":"Q14671","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
