3PU8
PHF2 Jumonji-NOG-Fe(II) complex
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE OXY A 1 |
| Chain | Residue |
| A | OGA2 |
| A | HOH58 |
| A | THR193 |
| A | HIS335 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE OXY B 2 |
| Chain | Residue |
| B | OGA1 |
| B | HOH31 |
| B | THR193 |
| B | HIS335 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 452 |
| Chain | Residue |
| A | SER198 |
| A | LYS232 |
| A | THR234 |
| A | HOH493 |
| A | HOH551 |
| A | HOH17 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 452 |
| Chain | Residue |
| B | PHE89 |
| B | ARG96 |
| B | PHE294 |
| B | HOH546 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 4 |
| Chain | Residue |
| B | PHE426 |
| B | LYS427 |
| B | HOH528 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 5 |
| Chain | Residue |
| B | HOH52 |
| B | LYS230 |
| B | HOH539 |
| B | HOH604 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 6 |
| Chain | Residue |
| B | LEU115 |
| B | GLY116 |
| B | LYS214 |
| B | HOH561 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 7 |
| Chain | Residue |
| A | ARG272 |
| A | HOH515 |
| B | ALA416 |
| B | ASP420 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 8 |
| Chain | Residue |
| A | PHE426 |
| A | LYS427 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 9 |
| Chain | Residue |
| A | LYS175 |
| A | ASP179 |
| B | LYS131 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 10 |
| Chain | Residue |
| A | GLU219 |
| A | ASN220 |
| A | HOH519 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 11 |
| Chain | Residue |
| A | LYS214 |
| A | LEU215 |
| A | TYR221 |
| A | HIS338 |
| A | SER339 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 12 |
| Chain | Residue |
| A | GLU92 |
| A | LEU93 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 13 |
| Chain | Residue |
| A | EDO14 |
| A | SER317 |
| A | LEU340 |
| A | SER341 |
| A | MET344 |
| A | HOH515 |
| site_id | BC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 14 |
| Chain | Residue |
| A | EDO13 |
| A | EDO15 |
| A | LEU340 |
| A | SER341 |
| A | VAL342 |
| A | GLU343 |
| A | MET344 |
| A | HOH520 |
| site_id | BC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 15 |
| Chain | Residue |
| A | EDO14 |
| A | SER339 |
| A | LEU340 |
| A | SER341 |
| A | VAL342 |
| A | HIS394 |
| A | GLY398 |
| A | ILE401 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 16 |
| Chain | Residue |
| A | ARG186 |
| A | VAL241 |
| A | LYS242 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 17 |
| Chain | Residue |
| B | MET346 |
| B | TYR349 |
| B | GLU350 |
| B | ARG353 |
| B | TRP409 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 18 |
| Chain | Residue |
| A | ASP179 |
| A | TYR182 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 20 |
| Chain | Residue |
| B | GLU119 |
| B | LEU215 |
| B | HIS394 |
| site_id | CC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE OGA B 1 |
| Chain | Residue |
| B | OXY2 |
| B | HOH31 |
| B | HOH54 |
| B | LEU238 |
| B | HIS249 |
| B | ASP251 |
| B | TYR259 |
| B | LYS266 |
| B | TYR321 |
| B | THR323 |
| B | HIS335 |
| B | FE454 |
| site_id | CC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE OGA A 2 |
| Chain | Residue |
| A | HIS249 |
| A | ASP251 |
| A | TYR259 |
| A | LYS266 |
| A | TYR321 |
| A | THR323 |
| A | HIS335 |
| A | FE453 |
| A | HOH481 |
| A | OXY1 |
| A | HOH58 |
| A | LEU238 |
| A | THR246 |
| site_id | CC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 453 |
| Chain | Residue |
| B | SER216 |
| B | TRP217 |
| B | VAL218 |
| B | LEU337 |
| B | HOH588 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 4 |
| Chain | Residue |
| A | SER216 |
| A | TRP217 |
| A | VAL218 |
| A | PHE336 |
| A | LEU337 |
| A | HOH498 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE B 454 |
| Chain | Residue |
| B | OGA1 |
| B | HIS249 |
| B | ASP251 |
| B | TYR321 |
| B | HOH545 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE A 453 |
| Chain | Residue |
| A | OGA2 |
| A | HIS249 |
| A | ASP251 |
| A | TYR321 |
| A | HOH475 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 454 |
| Chain | Residue |
| A | ASP133 |
| A | GLY134 |
| A | LEU135 |
| A | GLY136 |
| A | HOH469 |
| site_id | DC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 455 |
| Chain | Residue |
| A | SER275 |
| A | ILE278 |
| A | MET344 |
| A | ARG347 |
| site_id | DC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 12 |
| Chain | Residue |
| B | ASP133 |
| B | GLY134 |
| B | LEU135 |
| B | GLY136 |
| B | HOH473 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 13 |
| Chain | Residue |
| A | LYS304 |
| B | TYR152 |
| B | ARG201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 312 |
| Details | Domain: {"description":"JmjC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00538","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00538","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21167174","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
