3P4X

Helicase domain of reverse gyrase from Thermotoga maritima

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003916	molecular_function	DNA topoisomerase activity
A	0005524	molecular_function	ATP binding
A	0006265	biological_process	DNA topological change
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0003916	molecular_function	DNA topoisomerase activity
B	0005524	molecular_function	ATP binding
B	0006265	biological_process	DNA topological change

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 799

Chain	Residue
A	HOH32
A	HOH33
A	HOH34
A	HOH35
A	THR107
A	ADP800

---

site_id	AC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP A 800

Chain	Residue
A	PHE75
A	LYS77
A	ASP78
A	THR80
A	GLN83
A	THR102
A	GLY103
A	VAL104
A	GLY105
A	LYS106
A	THR107
A	THR108
A	MG799
A	HOH34
A	HOH35
A	PHE71

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 1

Chain	Residue
B	GLY105
B	THR108
B	ARG140

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	310
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_01125","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	54
Details	Region: {"description":"Insert region","evidences":[{"source":"PubMed","id":"23209025","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Motif: {"description":"DEAD box","evidences":[{"source":"HAMAP-Rule","id":"MF_01125","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21627332","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3P4X","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01125","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---